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Basic information

CohesinDB ID: CDBP00418157

Locus: chr21-35628178-35628897

Data sourse: GSE105004, GSE138405, GSE68388, GSE116344, GSE126990, GSE165895

Cell type: Hela-Kyoto, RH4, HeLa, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 80% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MYCN, SIN3A, XBP1, ZBTB48, SMAD3, STAT1, YY1, RUNX2, MYC, GATA4, GRHL3, GATA3, MAX, GATA1, ZNF143, IKZF1, CEBPB, TEAD1, EZH2, JUN, EP300, AR, GATA6, GATA2, REST, ZHX1, RNF2, BRD4, SMC3, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418157