- Basic information
- CohesinDB ID: CDBP00418160
- Locus: chr21-35632706-35633020
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Data sourse: GSE86191
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Cell type: HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 69%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, E2F7, MEIS2, XBP1, FOXA1, PBX2, ATF3, BMI1, NFIC, CHD7, PRDM1, CBFB, MYOG, ZNF629, TEAD1, NFE2L2, LMO2, ESR1, TP73, CTCF, JUN, TCF12, EP300, RFX5, CREB3, E2F1, ZNF528, TEAD4, GTF2F1, PDX1, EED, GLIS1, ZNF263, MYCN, TOP2A, HHEX, POU5F1, ZSCAN21, ZBTB48, SRF, HOXC5, ZBTB21, ERG, ASCL1, ONECUT1, MYC, SMARCA4, RAD21, LHX2, RXRA, PROX1, STAT3, NKX3-1, NFE2, RCOR1, VDR, NR3C1, ESRRA, CEBPB, CREB1, EZH2, ZHX2, KLF17, GATA2, FLI1, MAFG, SMC1A, EZH2phosphoT487, ZFX, POU4F2, SMAD3, CBX8, SMARCC1, MEF2A, RUNX2, GATA4, ZNF184, ARNT, NRF1, PBX4, DAXX, ATF2, PRDM9, PBX3, ZNF10, FOS, CDK8, MED1, ZEB1, SCRT2, C11orf30, SREBF2, MAFK, ATF7, ZHX1, SMC3, PAX7, ZNF283, ZNF316, FOXA2, CHD2, GTF2B, MAFF, MEF2C, RELA, JUNB, GATA3, TAL1, MAX, ZNF143, ZFP69B, KLF4, SP7, NR2F2, TP53, NFKB1, AR, PAX3-FOXO1, YAP1, EGLN2, ZNF366, RNF2, SCRT1, BRD4, JUND, BRCA1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:27000000-27025000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34875000-34900000~~chr21:35625000-35650000,
chr21:35400000-35425000~~chr21:35625000-35650000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35925000-35950000,
chr21:35625000-35650000~~chr21:36025000-36050000,