- Basic information
- CohesinDB ID: CDBP00418162
- Locus: chr21-35634449-35638495
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Data sourse: ENCSR000EFJ, GSE138405, ENCSR000HPG, ENCSR000BLY, GSE85526, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE116344, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: Hela-Kyoto, Fibroblast, RH4, HEKn, HeLa-S3, IMR-90, SK-N-SH, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 47%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOSL1, PGR, FOXA2, SOX2, SIN3A, SMAD3, FOXA1, CBX8, HOXB13, HOXC5, ERG, RELA, JUNB, ATF3, RUNX2, NFIC, GATA4, MYC, MCM3, PBX4, HIF1A, DAXX, NRF1, GATA3, GABPA, TAL1, MAX, PBX3, STAT3, FOS, NKX3-1, HDAC3, MED1, SFPQ, TLE3, NR3C1, CEBPB, CREB1, PIAS1, TP53, ESR1, JUN, TCF12, BRD2, SPI1, BAF155, AR, GATA6, GATA2, ARID1A, ASH2L, RNF2, BRD4, JUND, FOXP1, NFYB, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:27000000-27025000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34875000-34900000~~chr21:35625000-35650000,
chr21:34887508-34892091~~chr21:35642873-35644084,
chr21:35400000-35425000~~chr21:35625000-35650000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35925000-35950000,
chr21:35625000-35650000~~chr21:36025000-36050000,