- Basic information
- CohesinDB ID: CDBP00418165
- Locus: chr21-35646507-35647140
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MED1, NR3C1, CEBPB, ATF3, FOXA2, RUNX2, TOP2A, RAD21, XBP1, BRD4, MYOD1, MAX, CTCF
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:27000000-27025000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34692406-34694411~~chr21:35648041-35649435,
chr21:34875000-34900000~~chr21:35625000-35650000,
chr21:34887508-34892091~~chr21:35642873-35644084,
chr21:35400000-35425000~~chr21:35625000-35650000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35925000-35950000,
chr21:35625000-35650000~~chr21:36025000-36050000,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35925000-35950000,
chr21:35652140-35653632~~chr21:35931764-35934473,