- Basic information
- CohesinDB ID: CDBP00418168
- Locus: chr21-35652663-35653405
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Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE103477, GSE131606, GSE108869, GSE25021, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE67783, GSE86191, GSE138405, GSE101921, GSE116344, ENCSR703TNG, ENCSR000BLS, ENCSR000BMY, GSE55407, ENCSR000BTQ, GSE110061, GSE129526, GSE111913, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS
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Cell type: MDM, RH4, GM10847, GM2610, GM19240, HSPC, Liver, HuCC-T1, GM2630, GM12890, HeLa-S3, GM2255, GM18486, GM18526, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, THP-1, GM19099, MCF-7, GM12892, Hela-Kyoto, HCT-116, MCF-10A, Hep-G2, GM19238, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 17% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.633
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 71%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, SMC1A, CBX3, MYCN, ZNF534, WT1, ZNF574, YY1, ZBTB2, ATF3, MYC, CTCFL, RAD21, GRHL3, ATF4, MAX, PAX5, CEBPG, CEBPB, DIDO1, ESR1, L3MBTL2, GRHL2, CTCF, BRD2, GATA2, ZBTB7A, TRIM24, FLI1, ZNF350, EP400, SMC3, ZNF24, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
- Related loop:
chr21:27000000-27025000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34692406-34694411~~chr21:35648041-35649435,
chr21:34875000-34900000~~chr21:35625000-35650000,
chr21:35400000-35425000~~chr21:35625000-35650000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35925000-35950000,
chr21:35625000-35650000~~chr21:36025000-36050000,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35925000-35950000,
chr21:35652140-35653632~~chr21:35931764-35934473,