- Basic information
- CohesinDB ID: CDBP00418171
- Locus: chr21-35657970-35658714
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Data sourse: ENCSR000EFJ, GSE98367, ENCSR000HPG, ENCSR000BLY, GSE206145-NatGen2015, GSE68388, GSE103477, GSE111537, GSE116344, GSE165895
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Cell type: MDM, Fibroblast, RH4, HuCC-T1, IMR-90, SK-N-SH, OCI-AML-3, THP-1, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 61%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, CEBPA, MYCN, E2F7, RUNX1T1, SS18, MEIS1, FOXA2, ZNF692, SMAD3, MEF2C, CDK9, SMARCC1, KDM1A, TFAP4, RELA, ERG, RUNX2, NFIC, MYC, RAD21, RUNX3, GRHL3, PBX4, TCF4, DAXX, CBFB, ATF2, GATA3, MECOM, STAT3, MAX, CDK8, MED1, VDR, NR3C1, MAF, JMJD1C, CEBPB, TEAD1, TRIM28, MYB, KMT2A, TCF7L2, ETV1, LMO2, TP53, MLL, ESR1, TP73, GRHL2, CTCF, TCF12, SPI1, BCL11A, BHLHE40, AR, GATA2, REST, TRIM24, FLI1, BRD4, PHIP, TCF3, CLOCK, ZNF528, SMC3, KMT2B, MLLT1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops