- Basic information
- CohesinDB ID: CDBP00418172
- Locus: chr21-35663900-35665122
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Data sourse: GSE67783, ENCSR000BLY, GSE85526, GSE68388, GSE103477, GSE116344, GSE131606, GSE50893
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Cell type: MDM, RH4, HEKn, GM2588, SK-N-SH, HSPC, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, XBP1, FOXA1, PBX2, MLL4, ZFHX2, ATF3, NFIC, RUNX3, PAX5, MITF, MYOG, MAF, TEAD1, KLF6, ZNF217, ESR1, HNF1B, JUN, TCF12, EP300, DPF2, IRF4, RAD51, E2F1, TEAD4, ZNF92, TFAP2C, POU2F2, MTA2, ZBTB17, DUX4, MLLT3, ERG2, HOXC5, ASCL1, MYC, SMARCA4, RAD21, GRHL3, PROX1, STAT3, IKZF1, ARNTL, NR3C1, EZH2, GRHL2, SPI1, IRF1, GATA2, SIX2, RELB, ZNF554, RUNX1, SMC1A, SOX13, ZFX, SMAD3, ERG3, RUNX2, GATA4, ZNF184, PBX4, DAXX, PRDM9, PBX3, SNRNP70, TEAD3, TERF1, MYB, SCRT2, SETDB1, USF1, BCL11A, ATF7, POU2F3, PHIP, NCOR2, STAG1, EBF1, YY1, RELA, JUNB, GATA3, BATF, ZFP69B, KLF4, NCOA3, TP53, PKNOX1, MYOD1, EGR2, BRD2, ELF3, TBX21, BHLHE40, RXR, IKZF2, SCRT1, BRD4, JUND, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops