- Basic information
- CohesinDB ID: CDBP00418174
- Locus: chr21-35674767-35675879
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE25021, ENCSR917QNE, GSE138405, GSE112028, ENCSR703TNG, GSE116344, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE129526, ENCSR000EDE, GSE68388, GSE126990
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Cell type: MCF-7, H1-hESC, MDM, Hela-Kyoto, HCT-116, RH4, HeLa-S3, HUES64, Liver, SK-N-SH, HeLa-Tet-On, OCI-AML-3, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,SMC3ac
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 59%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, CBX1, SIN3A, ZFX, SS18, SMAD3, FOXA1, CDK9, HNF4G, ERG, YY1, RELA, MYC, CDK6, RUNX2, ONECUT1, RAD21, ARNT, DAXX, RXRA, GATA3, GABPA, TAL1, PBX3, STAT3, FOS, NR3C1, ESRRA, KLF4, PDX1, NR2F2, MYB, ETV1, ZMYM3, ESR1, HNF1B, KLF9, ELF3, CTCF, TCF12, BCL11A, SPI1, SP1, HNF4A, LMO1, IRF1, EP300, PAX8, GATA2, REST, RBM25, BRD4, PHIP, BCOR, FOXP1, JUND, HEXIM1-CDK9, STAG1
- Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000185917,
- Related loop:
chr21:34300000-34325000~~chr21:35675000-35700000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34350000-34375000~~chr21:35675000-35700000,
chr21:35510785-35512091~~chr21:35676592-35678756,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35925000-35950000,
chr21:35674462-35675960~~chr21:35839090-35841121,
chr21:35675000-35700000~~chr21:35775000-35800000,
chr21:35675000-35700000~~chr21:35825000-35850000,
chr21:35675000-35700000~~chr21:35925000-35950000,
chr21:35675000-35700000~~chr21:36025000-36050000,