- Basic information
- CohesinDB ID: CDBP00418175
- Locus: chr21-35676305-35677960
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE206145-NatGen2015, ENCSR000ECE, ENCSR703TNG, GSE25021, GSE116344, ENCSR917QNE
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Cell type: MCF-7, H1-hESC, Fibroblast, RH4, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ESRRA, HNF4A, RUNX2, RFX1, CREB1, ZFX, CTBP1, ESR1, HIF1A, NOTCH3, RXRA, FOXA1, GATA3, SOX11, CTCF, CDK9, ZNF143, SP1, BHLHE40
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000185917,
- Related loop:
chr21:34300000-34325000~~chr21:35675000-35700000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34350000-34375000~~chr21:35675000-35700000,
chr21:35510785-35512091~~chr21:35676592-35678756,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35925000-35950000,
chr21:35674462-35675960~~chr21:35839090-35841121,
chr21:35675000-35700000~~chr21:35775000-35800000,
chr21:35675000-35700000~~chr21:35825000-35850000,
chr21:35675000-35700000~~chr21:35925000-35950000,
chr21:35675000-35700000~~chr21:36025000-36050000,