- Basic information
- CohesinDB ID: CDBP00418181
- Locus: chr21-35696722-35697834
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE67783, GSE138405, ENCSR000BLY, GSE206145, ENCSR153HNT, GSE68388, GSE83726, GSE130135, GSE111537, GSE126990, GSE116344, ENCSR917QNE
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, RH4, HEK293T, SK-N-SH, K-562, Liver, OCI-AML-3, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
80% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 34%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, ZNF660, PATZ1, FOXA1, PBX2, HNRNPK, NFIC, ZFP64, ZBTB44, PRDM1, ZNF322, CHD7, RUNX3, MITF, ZNF467, MYOG, JMJD1C, TRIM28, ESR1, CTCF, TCF12, IRF4, TFAP2C, GLIS1, ZNF263, MYCN, TOP2A, KDM4C, ZBTB17, ZBTB48, SRF, SP4, ASCL1, MYC, SMARCA4, RAD21, RXRA, NKX2-1, GABPA, STAT3, ZNF398, NFE2, VDR, CEBPB, EZH2, FEZF1, SPI1, GATA2, FLI1, ZNF554, MYF5, RUNX1, NKX2-2, ZNF335, ZFX, ZNF770, PRDM10, RARA, CREBBP, ZNF35, ZNF384, GATA4, ZNF184, ARNT, NFIB, PBX3, MAFB, FOS, CDK8, MED1, MYB, SCRT2, ZNF3, TBX5, SP1, BCL11A, HNF4A, NKX2-5, PHIP, TCF3, SMC3, STAG1, MLLT1, CBFA2T2, MEIS1, ZNF692, ZSCAN16, ZNF30, WT1, ZNF574, CDK9, YY1, RELA, TCF4, HIF1A, ZFP36, GATA3, MAX, NRIP1, GATA1, TP53, MYOD1, BRD2, AR, PAX3-FOXO1, ZNF324, ZBTB42, HSF1, NCOR1, BRD4, SCRT1, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops