- Basic information
- CohesinDB ID: CDBP00418210
- Locus: chr21-35778799-35780766
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Data sourse: ENCSR000EFJ, GSE138405, GSE116344, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE112028, GSE130135, GSE111537, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: Hela-Kyoto, Fibroblast, RH4, HEK293T, HeLa-S3, IMR-90, SK-N-SH, HeLa-Tet-On, OCI-AML-3, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 49%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, ZNF391, PGR, ZNF496, ZNF660, E2F7, PATZ1, FOXA1, INSM2, NFIC, ATF3, ZNF362, RUNX3, PRDM1, CHD7, CBFB, ZNF189, MITF, ZNF629, JMJD1C, TEAD1, NFE2L2, ESR1, MLL, TP73, USF2, CTCF, JUN, TCF12, EP300, GATA6, TRIM24, RFX5, DEK, ZNF528, TEAD4, KMT2B, GTF2F1, GLIS1, BRD3, MYCN, ZSCAN21, ZBTB17, ZBTB48, STAT1, HIC1, ZBTB21, MYC, SMARCA4, TSHZ1, ARID1B, RAD21, GRHL3, RXRA, BATF3, STAT3, UBN1, ZNF398, RCOR1, NFE2, ZNF639, ARNTL, VDR, NR3C1, CEBPB, EZH2, KLF8, GRHL2, ZHX2, SPI1, ZNF664, HDAC2, GATA2, ZNF554, RUNX1, MAFG, LDB1, AFF4, SMAD3, PCBP2, ZFP37, ZNF549, PRDM10, SMARCC1, MEF2A, ZNF35, ZNF133, RUNX2, GATA4, OSR2, ZNF184, SP3, NRF1, PBX4, DAXX, ZBTB10, PRDM9, ZEB2, ZNF518A, PBX3, ZNF10, FOS, CDK8, MED1, ZXDB, MYB, SCRT2, SETDB1, HIF2A, MAFK, USF1, BCL11A, REST, ARID1A, RBM25, ZHX1, PHIP, SMC3, ELL2, MLLT1, ZNF394, CHD2, SS18, ZNF600, ZNF692, GTF2B, MAFF, ZNF30, WT1, MEF2C, CDK9, RELA, JUNB, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, ZFP69B, SP7, NR2F2, TCF7L2, KDM5B, TP53, MED, ZNF334, BRD2, ZNF843, AR, ZNF324, ZNF366, ZNF280D, RNF2, NOTCH3, SCRT1, BRD4, JUND, MAZ, ZSCAN23, BRCA1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops