Browse_each

Basic information

CohesinDB ID: CDBP00418222

Locus: chr21-35826438-35826754

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 70%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, SS18, SOX2, ZSCAN16, FOXA1, MLL4, SMARCC1, RELA, SMARCA4, ARNT, TCF4, PROX1, GATA3, TAL1, PBX3, STAT3, SPIB, CDK8, TERF2, CDX2, NR3C1, TCF7L2, ESR1, TP53, BRD2, TCF12, SPI1, HNF4A, AR, GATA2, BRD4, PHIP, JUND, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,RCAN1,RUNX1,CLIC6,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418222