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Basic information

CohesinDB ID: CDBP00418223

Locus: chr21-35829136-35829658

Data sourse: GSE105028, GSE116344, GSE83726, GSE206145

Cell type: RH4, HEK293T, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 59%, "14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, BCL6, SMC1A, BRD3, SOX2, ZFX, ZNF692, XBP1, ZBTB48, FOXA1, ERG3, ERG2, HOXB13, MLL4, ZNF28, TFAP4, YY1, RELA, ASCL1, NOTCH1, ATF3, MYC, NFIC, SMARCA4, RAD21, SP140, ARNT, PROX1, GATA3, STAT3, MAX, MZF1, TAL1, FOS, ZNF143, CDX2, ZNF281, NCOA3, TRIM28, MYB, SCRT2, PIAS1, TCF7L2, KDM5B, TP53, ESR1, OCA2, L3MBTL2, FEZF1, BCL6B, BRD2, ELF3, USF1, SPI1, BCL11A, CTCF, GATA2, SIX2, BRD4, PHIP, JUND, SCRT1

Target gene symbol (double-evidenced CRMs): SMIM11A,CLIC6,RUNX1,RCAN1,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418223