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Basic information

CohesinDB ID: CDBP00418224

Locus: chr21-35831642-35832191

Data sourse: GSE86191, GSE116344, GSE68388

Cell type: RH4, HCT-116, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 53%, "14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NCOA2, SMC1A, BRD1, TBL1X, POU5F1, ZFX, ZNF317, WT1, MAFF, ERG3, ERG2, ZFHX2, YY1, RELA, ATF3, RUNX2, MCM3, SP140, ARNT, HIF1A, GRHL3, PROX1, MAX, XRCC5, SPIB, ZNF143, HNRNPH1, STAT5B, RBM39, EZH2, EGR2, CTCF, SPI1, AR, GATA6, SIX2, HSF1, BRD4, MAZ, SMC3, EED

Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,RCAN1,CLIC6,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418224