- Basic information
- CohesinDB ID: CDBP00418228
- Locus: chr21-35836412-35837584
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Data sourse: ENCSR000BLD, GSE86191, GSE138405, GSE129526, GSE25021, ENCSR000BLY, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, GSE206145, GSE83726, GSE116344, GSE126990, GSE50893, ENCSR000ECS
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Cell type: MCF-7, GM12892, GM2630, Fibroblast, H1-hESC, HCT-116, Hela-Kyoto, RH4, RPE, SNYDER, GM19240, GM12891, GM2588, HeLa-S3, SK-N-SH, GM18486, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 65%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TOP2A, SS18, RAD21, ESR1, BRD4, CTCF, ZNF143, STAG1
- Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,SETD4,CLIC6,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35825000-35850000,
chr21:34500000-34525000~~chr21:35825000-35850000,
chr21:34675000-34700000~~chr21:35825000-35850000,
chr21:34700000-34725000~~chr21:35825000-35850000,
chr21:34725000-34750000~~chr21:35825000-35850000,
chr21:34750000-34775000~~chr21:35825000-35850000,
chr21:34775000-34800000~~chr21:35825000-35850000,
chr21:34850000-34875000~~chr21:35825000-35850000,
chr21:34875000-34900000~~chr21:35825000-35850000,
chr21:34887476-34892097~~chr21:35838896-35841159,
chr21:34887508-34892091~~chr21:35839117-35841138,
chr21:34887518-34891075~~chr21:35839484-35840994,
chr21:34887552-34891083~~chr21:35839536-35841080,
chr21:34888177-34892032~~chr21:35838708-35841092,
chr21:34888362-34892029~~chr21:35838891-35841138,
chr21:34889149-34891526~~chr21:35839251-35841748,
chr21:34889184-34892059~~chr21:35838738-35841127,
chr21:34889188-34892063~~chr21:35839343-35841742,
chr21:34889223-34891142~~chr21:35839105-35841278,
chr21:34889251-34892128~~chr21:35838780-35841161,
chr21:34889270-34892070~~chr21:35838715-35841129,
chr21:34889367-34892315~~chr21:35838730-35841126,
chr21:34889375-34890944~~chr21:35839523-35841115,
chr21:34889427-34892109~~chr21:35839090-35841121,
chr21:34975000-35000000~~chr21:35825000-35850000,
chr21:35000000-35025000~~chr21:35825000-35850000,
chr21:35025000-35050000~~chr21:35825000-35850000,
chr21:35050107-35052241~~chr21:35839295-35841164,
chr21:35050531-35052287~~chr21:35839087-35841133,
chr21:35050674-35052154~~chr21:35839468-35841150,
chr21:35100000-35125000~~chr21:35825000-35850000,
chr21:35125000-35150000~~chr21:35825000-35850000,
chr21:35200000-35225000~~chr21:35825000-35850000,
chr21:35203018-35206280~~chr21:35838646-35841847,
chr21:35250000-35275000~~chr21:35825000-35850000,
chr21:35350000-35375000~~chr21:35825000-35850000,
chr21:35375000-35400000~~chr21:35825000-35850000,
chr21:35398212-35401570~~chr21:35839090-35841121,
chr21:35399380-35401604~~chr21:35838708-35841092,
chr21:35400000-35425000~~chr21:35825000-35850000,
chr21:35425000-35450000~~chr21:35825000-35850000,
chr21:35431177-35432375~~chr21:35838785-35841072,
chr21:35431208-35432504~~chr21:35838718-35841129,
chr21:35500000-35525000~~chr21:35825000-35850000,
chr21:35507719-35509586~~chr21:35838715-35841129,
chr21:35507729-35509950~~chr21:35838730-35841126,
chr21:35507734-35509545~~chr21:35838780-35841161,
chr21:35510787-35512464~~chr21:35838715-35841129,
chr21:35525000-35550000~~chr21:35825000-35850000,
chr21:35575000-35600000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35674462-35675960~~chr21:35839090-35841121,
chr21:35675000-35700000~~chr21:35825000-35850000,
chr21:35725000-35750000~~chr21:35825000-35850000,
chr21:35825000-35850000~~chr21:35925000-35950000,
chr21:35825000-35850000~~chr21:36025000-36050000,
chr21:35839105-35841278~~chr21:36027276-36029656,
chr21:35839117-35841138~~chr21:35939344-35941327,
chr21:35839251-35841748~~chr21:36027342-36029650,
chr21:35839536-35841080~~chr21:36112039-36113944,