- Basic information
- CohesinDB ID: CDBP00418232
- Locus: chr21-35852978-35854102
-
Data sourse: GSE206145-NatGen2015, GSE165895
-
Cell type: Fibroblast, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 46%,
"14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, ZNF239, POU5F1, TOP2A, SOX2, SS18, ZFX, ERG2, RELA, GATA4, GATA3, TAL1, FOS, GATA1, MED1, NR3C1, CEBPB, KLF4, CREB1, EZH2, BHLHE40, GATA2, ZNF548, BRD4, NR1H3
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,SETD4,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35825000-35850000,
chr21:34350000-34375000~~chr21:35850000-35875000,
chr21:34500000-34525000~~chr21:35825000-35850000,
chr21:34675000-34700000~~chr21:35825000-35850000,
chr21:34675000-34700000~~chr21:35850000-35875000,
chr21:34700000-34725000~~chr21:35825000-35850000,
chr21:34725000-34750000~~chr21:35825000-35850000,
chr21:34750000-34775000~~chr21:35825000-35850000,
chr21:34775000-34800000~~chr21:35825000-35850000,
chr21:34775000-34800000~~chr21:35850000-35875000,
chr21:34850000-34875000~~chr21:35825000-35850000,
chr21:34875000-34900000~~chr21:35825000-35850000,
chr21:34975000-35000000~~chr21:35825000-35850000,
chr21:35000000-35025000~~chr21:35825000-35850000,
chr21:35025000-35050000~~chr21:35825000-35850000,
chr21:35100000-35125000~~chr21:35825000-35850000,
chr21:35125000-35150000~~chr21:35825000-35850000,
chr21:35200000-35225000~~chr21:35825000-35850000,
chr21:35250000-35275000~~chr21:35825000-35850000,
chr21:35350000-35375000~~chr21:35825000-35850000,
chr21:35375000-35400000~~chr21:35825000-35850000,
chr21:35400000-35425000~~chr21:35825000-35850000,
chr21:35425000-35450000~~chr21:35825000-35850000,
chr21:35500000-35525000~~chr21:35825000-35850000,
chr21:35525000-35550000~~chr21:35825000-35850000,
chr21:35575000-35600000~~chr21:35825000-35850000,
chr21:35625000-35650000~~chr21:35825000-35850000,
chr21:35650000-35675000~~chr21:35825000-35850000,
chr21:35675000-35700000~~chr21:35825000-35850000,
chr21:35725000-35750000~~chr21:35825000-35850000,
chr21:35825000-35850000~~chr21:35925000-35950000,
chr21:35825000-35850000~~chr21:36025000-36050000,
chr21:35850000-35875000~~chr21:35950000-35975000,
chr21:35850000-35875000~~chr21:35975000-36000000,
chr21:35850000-35875000~~chr21:36000000-36025000,
chr21:35850000-35875000~~chr21:36025000-36050000,
chr21:35850000-35875000~~chr21:36100000-36125000,