- Basic information
- CohesinDB ID: CDBP00418235
- Locus: chr21-35861535-35862042
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Data sourse: GSE206145-NatGen2015, ENCSR000BLY
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Cell type: Fibroblast, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, NANOG, POU2F2, POU5F1, EZH2phosphoT487, SS18, ZFX, POU4F2, ZNF317, XBP1, ZBTB48, PCBP2, SMAD3, FOXA1, ERG3, ERG2, HOXB13, ZFHX2, ERG, HNRNPK, YY1, RELA, NFIC, MYC, GATA4, ZNF184, RAD21, ARNT, GRHL3, PBX4, HIF1A, GATA3, GABPA, STAT3, PBX3, MAX, NKX3-1, FOS, ZNF143, TERF2, HDAC3, MED1, TLE3, CEBPB, TRIM28, PIAS1, EZH2, KDM5B, TP53, OCA2, ZNF334, EGR2, CTCF, TCF12, BAF155, SPI1, EP300, MNT, AR, GATA6, HDAC2, GATA2, E2F6, ZNF366, NCOR1, JUND, BRD4, FOXP1, ZNF350, TEAD4, AHR, EED
- Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RUNX1,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:35850000-35875000,
chr21:34675000-34700000~~chr21:35850000-35875000,
chr21:34775000-34800000~~chr21:35850000-35875000,
chr21:35850000-35875000~~chr21:35950000-35975000,
chr21:35850000-35875000~~chr21:35975000-36000000,
chr21:35850000-35875000~~chr21:36000000-36025000,
chr21:35850000-35875000~~chr21:36025000-36050000,
chr21:35850000-35875000~~chr21:36100000-36125000,