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Basic information

CohesinDB ID: CDBP00418236

Locus: chr21-35873964-35875028

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE93080, GSE206145-GSE177045, GSE72082, GSE138405, ENCSR000BLY, GSE105028, ENCSR000ECE, GSE68388, ENCSR703TNG, GSE25021, GSE116344, GSE97394

Cell type: MCF-7, H1-hESC, Hela-Kyoto, RH4, GM12878, HUES64, SK-N-SH, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, SMC1A, NANOG, FOXA2, POU5F1, MAFF, FOXA1, ZNF574, CBX8, HOXB13, ERG, RELA, CREBBP, ZNF384, MYC, RAD21, PRDM1, HIF1A, GATA3, GABPA, NRIP1, ZNF143, NR3C1, CEBPB, ZNF750, TEAD3, NR2F2, TEAD1, NCOA3, PIAS1, EZH2, ESR1, TRPS1, CTCF, MAFK, SPI1, AR, ZNF257, GATA2, IRF4, EGLN2, HSF1, PCGF2, FOXP1, STAG1

Target gene symbol (double-evidenced CRMs): CLIC6,SMIM11A,RUNX1,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00418236