- Basic information
- CohesinDB ID: CDBP00418245
- Locus: chr21-35905009-35906403
-
Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE25021, ENCSR917QNE, ENCSR000DZP, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE206145-NatGen2015, ENCSR703TNG, GSE116344, GSE98367, ENCSR879KXD, ENCSR000ECE, GSE97394, GSE129526, ENCSR000EDE, GSE83726, GSE126990, GSE50893
-
Cell type: MCF-7, GM2630, H1-hESC, Fibroblast, HCT-116, Hela-Kyoto, MDM, RH4, GM12878, HeLa-S3, HUES64, SK-N-SH, K-562, Liver, HSPC, Macrophage, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.811
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: GLIS1, TRIM25, FOSL1, SMC1A, PPARG, CEBPA, ZNF263, FOXA2, CHD8, TBL1X, ZFX, ZNF534, XBP1, ZNF600, ZBTB48, WT1, STAT1, ZSCAN5A, GTF2B, MAFF, ZNF823, ERG2, ERG, YY1, RELA, USP7, ETS1, RUNX2, MYC, ATF3, EZH1, MCM3, SP140, GRHL3, HIF1A, RAD21, ARNT, RXRA, ATF2, BATF, TAL1, APC, TP63, MAFB, FOS, CDK8, MED1, CEBPB, TERF1, SCRT2, NR2F1, EZH2, ESR1, OCA2, TP53, BMPR1A, GRHL2, ZNF334, MAFG, C11orf30, CTCF, JUN, MAFK, SPI1, BCL11A, AR, IRF1, GATA2, ARID1A, RXR, IRF4, EGR1, ATF7, NCOR1, NOTCH3, BRD4, JUND, SCRT1, ZNF528, MAZ, SMC3, STAG1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops