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Basic information

CohesinDB ID: CDBP00418249

Locus: chr21-35924052-35924310

Data sourse: GSE111913, GSE67783, GSE86191

Cell type: RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, ZNF660, MEIS2, XBP1, HNF1A, FOXA1, PBX2, RXRB, MLL4, ATF3, ZFP64, CHD7, CBFB, MECOM, MITF, CDX2, ZNF629, JMJD1C, MYOG, TRIM28, KLF6, MCM7, RCOR2, ESR1, HNF1B, TP73, OCA2, MLL, USF2, CTCF, JUN, TCF12, EP300, ZNF695, SOX5, SOX4, TRIM24, IRF4, CREB3, RAD51, E2F1, ZNF528, TEAD4, KMT2B, FOXA3, GATAD2A, TFAP2C, RBPJ, GLIS1, POU2F2, CHD8, MYCN, POU5F1, CDK7, RUNX1T1, TOP2A, ZSCAN21, ZBTB17, MTA2, ZNF317, GATAD1, SAP130, ERG2, ARID3A, ERG, ZBTB21, HOXC5, CHD4, PBX1, ASCL1, ETS1, MYC, MCM5, SMARCA4, HOMEZ, RAD21, GRHL3, PROX1, NKX2-1, STAT3, XRCC5, SOX10, UBN1, ZNF614, RCOR1, NFE2, ZNF639, DACH1, VDR, ARNTL, NR3C1, CEBPB, LEF1, NR2F6, KMT2A, CREB1, EZH2, ZHX2, SPI1, TFE3, MIXL1, IRF1, ZNF257, KLF17, GATA2, ZNF644, FLI1, DRAP1, ZGPAT, MRTFB, NCOA2, ZNF554, NFYB, NFIL3, ATF1, ETV5, RUNX1, THAP11, BCL6, CEBPA, AFF4, ZFX, SIN3A, FIP1L1, SOX13, SMAD3, ERG3, SP5, SMARCC1, RARA, ZNF35, ZBTB2, NOTCH1, RUNX2, CDK6, OSR2, ZNF184, SP3, PBX4, DAXX, ARNT, NRF1, HMGB2, ZNF48, SMAD4, FOXM1, PBX3, MAFB, FOS, CDK8, CHD1, MED1, GMEB1, TEAD3, ZEB1, CEBPD, MYB, SUPT16H, ZNF3, KLF9, USF1, BCL11A, HNF4A, IKZF5, REST, ASH2L, HOXA9, PHIP, TCF3, FOXP1, SMC3, ELL2, STAG1, ZNF394, PPARG, FOXA2, SAFB, EBF1, MEIS1, SS18, CREM, ZNF600, MIER2, GTF2B, WT1, ZNF30, ZNF574, MEF2C, TCF7, CDK9, ZNF580, KDM1A, YY1, RELA, ZNF19, ZNF222, JUNB, ZFP36, ZIC2, GATA3, TAL1, MAX, ZNF143, GATA1, PLAG1, CEBPG, KLF4, SP7, BCL11B, NR2F2, GFI1B, TCF7L2, ZNF768, KDM5B, TP53, PKNOX1, MED, ZNF334, NFKB1, MYOD1, PHOX2B, BRD2, ELF3, KAT8, PHF5A, BHLHE40, PAX3-FOXO1, AR, HEXIM1, HSF1, ZBTB26, NOTCH3, BRD4, JUND, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670,

eachgene

Deatailed information for cohesin site CDBP00418249