- Basic information
- CohesinDB ID: CDBP00418254
- Locus: chr21-35946138-35946776
-
Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, GSE165895
-
Cell type: RPE, Fibroblast, HCT-116, Monocytes, HSPC, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 60%,
"14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, PAX7, FOSL1, CBFA2T2, MAFG, CHD8, FOXA2, ZNF263, MYCN, ZFX, ZNF534, CTBP1, XBP1, MAFF, ZBTB48, ZSCAN5A, WT1, ERG3, YY1, RELA, ZNF35, RUNX2, GATA4, ARID1B, ARNT, GATA3, ATF2, ZEB2, TAL1, CBFA2T3, FOXM1, XRCC5, GATA1, FOS, RCOR1, NFE2, NR2F6, CHD1, HNRNPH1, NR2F2, PML, SCRT2, NR2F1, TFAP2C, EZH2, ZBTB6, KLF9, C11orf30, PHOX2B, CTCF, TCF12, BCL11A, SPI1, IRF1, GATA6, DPF2, ZBTB7A, TRIM24, ATF7, FLI1, NCOR1, SCRT1, JUND, MAZ, TEAD4, ZNF24, STAG1, ZNF316, EED
- Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RCAN1,CLIC6,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:33925000-33950000~~chr21:35925000-35950000,
chr21:34350000-34375000~~chr21:35925000-35950000,
chr21:34350000-34375000~~chr21:35950000-35975000,
chr21:34500000-34525000~~chr21:35925000-35950000,
chr21:34500000-34525000~~chr21:35950000-35975000,
chr21:34625000-34650000~~chr21:35925000-35950000,
chr21:34625000-34650000~~chr21:35950000-35975000,
chr21:34650000-34675000~~chr21:35925000-35950000,
chr21:34675000-34700000~~chr21:35925000-35950000,
chr21:34675000-34700000~~chr21:35950000-35975000,
chr21:34700000-34725000~~chr21:35925000-35950000,
chr21:34725000-34750000~~chr21:35925000-35950000,
chr21:34750000-34775000~~chr21:35925000-35950000,
chr21:34775000-34800000~~chr21:35925000-35950000,
chr21:34850000-34875000~~chr21:35925000-35950000,
chr21:34875000-34900000~~chr21:35925000-35950000,
chr21:35025000-35050000~~chr21:35925000-35950000,
chr21:35050000-35075000~~chr21:35925000-35950000,
chr21:35050211-35052170~~chr21:35939705-35941268,
chr21:35050328-35052241~~chr21:35939333-35941309,
chr21:35050353-35052253~~chr21:35939344-35941327,
chr21:35050390-35052306~~chr21:35939302-35941416,
chr21:35050457-35052285~~chr21:35939398-35941355,
chr21:35100000-35125000~~chr21:35925000-35950000,
chr21:35200000-35225000~~chr21:35925000-35950000,
chr21:35250000-35275000~~chr21:35925000-35950000,
chr21:35253661-35255186~~chr21:35939302-35941416,
chr21:35399885-35401612~~chr21:35939344-35941327,
chr21:35400000-35425000~~chr21:35925000-35950000,
chr21:35425000-35450000~~chr21:35950000-35975000,
chr21:35431152-35432481~~chr21:35939353-35941240,
chr21:35500000-35525000~~chr21:35925000-35950000,
chr21:35507735-35509518~~chr21:35939353-35941240,
chr21:35600000-35625000~~chr21:35925000-35950000,
chr21:35625000-35650000~~chr21:35925000-35950000,
chr21:35650000-35675000~~chr21:35925000-35950000,
chr21:35675000-35700000~~chr21:35925000-35950000,
chr21:35825000-35850000~~chr21:35925000-35950000,
chr21:35839117-35841138~~chr21:35939344-35941327,
chr21:35850000-35875000~~chr21:35950000-35975000,
chr21:35885539-35887170~~chr21:35939398-35941355,
chr21:35885577-35887971~~chr21:35939344-35941327,
chr21:35925000-35950000~~chr21:36025000-36050000,
chr21:35925000-35950000~~chr21:36100000-36125000,
chr21:35950000-35975000~~chr21:36075000-36100000,
chr21:35950000-35975000~~chr21:36100000-36125000,
chr21:7800000-7825000~~chr21:35925000-35950000,