Browse_each

Basic information

CohesinDB ID: CDBP00418255

Locus: chr21-35953385-35954030

Data sourse: ENCSR167MTG, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR000BLS, ENCSR054FKH, GSE68388, ENCSR000EDW, GSE115602

Cell type: MCF-7, HuCC-T1, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, HMG20A, HNF1A, FOXA1, RBFOX2, RXRB, KDM3A, TFAP4, TSC22D4, THRB, NFIC, ZFP64, MXD4, CDX2, TEAD1, ELF1, KLF6, KLF10, RCOR2, ESR1, OCA2, ZNF217, MBD4, JUN, CTCF, TCF12, EP300, BAF155, L3MBTL4, SOX5, GATA6, DPF2, SOX4, DMAP1, RFX5, SOX6, PRKDC, ZNF528, RFX3, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, TFAP2C, NANOG, HHEX, CTBP1, GATAD1, SAP130, GMEB2, ARID3A, HNF4G, ERG, SMARCC2, ETS1, MYC, HOMEZ, ARID1B, RAD21, RXRA, NKX2-1, FOXK2, GABPA, STAT3, ZNF614, XRCC5, IKZF1, MIER3, TCF25, NR2F6, DNMT3B, NR3C1, ZNF750, ESRRA, CEBPB, CREB1, EZH2, TBL1XR1, WDR5, GRHL2, ZNF652, GABPB1, ZHX2, HES1, TFE3, MIXL1, HBP1, IRF1, HDAC2, GATA2, SSRP1, ZNF644, MXD3, FLI1, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, CBX1, SOX13, SIN3A, SMAD3, TBX3, SP5, SMARCC1, MYBL2, RARA, PRPF4, NFYC, CREBBP, GATA4, GR, PBX4, ARNT, DAXX, ZNF48, PRDM9, SMAD4, FOXM1, FOS, HMGXB4, MED1, TEAD3, CEBPD, PIAS1, ZNF3, NCOA1, MBD1, RBM22, SP1, TFAP2A, NIPBL, HNF4A, IKZF5, REST, ASH2L, FOXP1, ETV4, SKI, PPARG, FOXA2, CREM, MIER2, TCF7, ZNF580, HOXB13, FOXO3, KDM1A, ZKSCAN1, RELA, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, TLE3, KLF4, CEBPG, NCOA3, NR2F2, ELF3, PHF5A, KAT8, NFKBIZ, AR, ARID4B, BHLHE40, EGLN2, HSF1, ZBTB26, BRD4, JUND, CUX1, SMAD4.1D12, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): CLIC6,SMIM11A,RCAN1,SETD4,CBR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000185917, ENSG00000159228,

eachgene

Deatailed information for cohesin site CDBP00418255