- Basic information
- CohesinDB ID: CDBP00418258
- Locus: chr21-35963973-35964518
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Data sourse: GSE138405, GSE165895
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Cell type: Hela-Kyoto, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, HMG20A, MEIS2, FOXA1, RBFOX2, PBX2, SNAPC1, TRIM28, BCLAF1, SMAD5, ESR1, EP300, E4F1, BAF155, MNT, ZNF157, SOX5, DDX20, E2F1, ZNF350, TEAD4, GATAD2A, STAT1, ZNF485, TBP, ERG, GRHL3, FOXK2, XRCC5, IKZF1, RCOR1, NR2F6, CEBPB, CREB1, EZH2, GRHL2, SPI1, IRF1, HDAC2, GATA2, NFIL3, NFYB, ATF1, GTF2A2, BCL6, CEBPA, HDAC1, SOX13, SIN3A, AFF4, ERG3, SMARCC1, RARA, RUNX2, ARNT, NRF1, ATF2, SMAD4, NFYA, PBX3, SP2, FOS, SUPT5H, MED1, PML, ZNF680, ZMYM3, TAF7, L3MBTL2, USF1, SP1, RBM25, MBD2, ELL2, NFATC3, NELFA, FOXA2, MTA3, CREM, GTF2B, ZBTB33, KDM1A, RELA, NEUROD1, HIF1A, GATA3, MAX, ZNF449, GATA1, HAND2, CEBPG, PKNOX1, ELF3, AR, TAF1, RNF2, JUND, BRD4, ILF3
- Target gene symbol (double-evidenced CRMs): SMIM11A,RCAN1,CBR1,SETD4,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000185917,
ENSG00000159228,
- Related loop:
chr21:34350000-34375000~~chr21:35950000-35975000,
chr21:34500000-34525000~~chr21:35950000-35975000,
chr21:34625000-34650000~~chr21:35950000-35975000,
chr21:34675000-34700000~~chr21:35950000-35975000,
chr21:35425000-35450000~~chr21:35950000-35975000,
chr21:35850000-35875000~~chr21:35950000-35975000,
chr21:35950000-35975000~~chr21:36075000-36100000,
chr21:35950000-35975000~~chr21:36100000-36125000,