- Basic information
- CohesinDB ID: CDBP00418260
- Locus: chr21-35968775-35968887
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 59%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MED1, MYC, IRF4, BRD4, CDK9, ZNF596
- Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,CBR1,RCAN1,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000185917,
ENSG00000159228,
- Related loop:
chr21:34350000-34375000~~chr21:35950000-35975000,
chr21:34500000-34525000~~chr21:35950000-35975000,
chr21:34625000-34650000~~chr21:35950000-35975000,
chr21:34675000-34700000~~chr21:35950000-35975000,
chr21:35425000-35450000~~chr21:35950000-35975000,
chr21:35850000-35875000~~chr21:35950000-35975000,
chr21:35950000-35975000~~chr21:36075000-36100000,
chr21:35950000-35975000~~chr21:36100000-36125000,