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Basic information

CohesinDB ID: CDBP00418262

Locus: chr21-35976923-35977297

Data sourse: ENCSR000BLD, ENCSR167MTG, GSE72082, GSE86191, GSE116868, ENCSR000BLS, ENCSR054FKH, ENCSR153HNT

Cell type: H1-hESC, HCT-116, MB157, Hep-G2, K-562

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 86% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 42%, "14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, POU2F2, BCL6, TRIM25, FOXA2, POU5F1, EBF1, CRY1, SOX13, ZNF534, ZFX, MYCN, ZNF263, ZBTB48, WT1, SMC1A, FOXA1, XBP1, ZNF662, ERG, ZNF19, YY1, RARA, RELA, AHR, RUNX2, MYC, GATA4, ZNF2, RUNX3, SP140, GRHL3, RAD21, ZNF48, PRDM9, SMAD4, APC, GATA1, ZNF143, CDK8, JMJD1C, TEAD3, TEAD1, NCOA3, CHD8, ESR1, OCA2, MYOD1, ELF3, CTCF, SPI1, EP300, TFE3, HNF4A, AR, CBFA2T2, ZNF644, ZBTB26, DRAP1, BRD4, PHIP, MAZ, SMC3, ZNF24, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418262