- Basic information
- CohesinDB ID: CDBP00418266
- Locus: chr21-35983170-35983412
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Data sourse: GSE111913, ENCSR153HNT, GSE86191
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Cell type: K-562, RT-112, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
86% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 52%,
"15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, NANOG, POU2F2, FOXA2, MYCN, ZNF263, ZFX, DUX4, SMAD3, ZNF616, FOXA1, WT1, CBX8, HOXB13, ZNF300, ERG, RELA, RUNX2, MYC, SMARCA4, OSR2, GRHL3, NKX2-1, GABPA, SMAD4, MITF, TEAD3, TRIM28, EZH2, ESR1, OCA2, GRHL2, ZNF334, MYOD1, BRD2, CTCF, BAF155, AR, GATA2, ZNF479, IRF4, MXD3, ASH2L, ZBTB26, BRD4, TEAD4, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34700000-34725000~~chr21:35975000-36000000,
chr21:34850000-34875000~~chr21:35975000-36000000,
chr21:34875000-34900000~~chr21:35975000-36000000,
chr21:34950000-34975000~~chr21:35975000-36000000,
chr21:35507719-35509586~~chr21:35984012-35986224,
chr21:35507734-35509545~~chr21:35984106-35986257,
chr21:35850000-35875000~~chr21:35975000-36000000,
chr21:35875000-35900000~~chr21:35975000-36000000,