Deatailed information for cohesin site CDBP00418270

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  • Basic information
  • CohesinDB ID: CDBP00418270
  • Locus: chr21-35991211-35992040
  • Data sourse: GSE67783, GSE86191, GSE72082, GSE206145-NatGen2015, GSE25021
  • Cell type: Fibroblast, HCT-116, HSPC, Hep-G2
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.956
  • Subunit: SA1,Rad21,SA2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 86% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "14_ReprPCWk": 53%, "15_Quies": 36%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, PGR, ZNF195, HMG20A, LCORL, ZNF621, NME2, MEIS2, XBP1, FOXA1, SUZ12, MLL4, ZFHX2, TFAP4, HDGF, ZNF274, BMI1, NFIC, ATF3, RUNX3, PRDM1, ZNF444, CBFB, CDC5L, KLF5, TEAD1, BCLAF1, KLF6, ESR1, OCA2, HNF1B, TP73, ZIK1, CTCF, TCF12, EP300, E4F1, ARID5B, MNT, LMO1, SOX5, GATA6, TRIM24, IRF4, ZNF512B, ZNF776, TEAD4, FOXA3, GATAD2A, PLRG1, EHMT2, EED, GLIS1, YBX1, NANOG, POU2F2, ZNF239, CDK7, KDM4C, ID3, CTBP1, ZBTB48, ZSCAN5A, STAT1, NONO, SAP130, DDX5, ERG2, PBX1, MCM5, MYC, RFX1, HOMEZ, RAD21, ARID1B, GRHL3, PROX1, NKX2-1, STAT3, ZNF614, XRCC5, IKZF1, RCOR1, ZNF639, ESRRA, SRSF3, CEBPB, CREB1, EZH2, ARHGAP35, GRHL2, SPI1, HES1, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, MXD3, ZNF785, SALL2, RUNX1, SMC1A, BCL6, HDAC1, CEBPA, ZNF707, EZH2phosphoT487, SOX13, ZFX, ZNF534, NKX2-2, SMAD3, ERG3, NFXL1, TRIM22, ZNF18, RARA, CREBBP, ZBTB2, NOTCH1, ZNF169, RUNX2, GATA4, ZNF184, NFIB, ARNT, ZBTB10, ATF2, SMAD4, ZEB2, CBFA2T3, CDK8, MED1, TEAD3, PML, CEBPD, MYB, SCRT2, ZMYM3, NCOA1, L3MBTL2, STAT5A, BCL11A, NIPBL, HNF4A, ZNF479, RBM25, ATF7, HNRNPLL, ZNF548, BCOR, FOXP1, TCF3, SMC3, STAG1, MLLT1, CBFA2T2, FOXA2, MTA3, ZNF207, TBL1X, MAFF, ZNF662, TCF7, CDK9, ZNF580, ZKSCAN1, KDM1A, RELA, TARDBP, ZNF148, ZNF521, MCM3, SP140, HIF1A, ZNF311, GATA3, TAL1, MAX, GATA1, PLAG1, CEBPG, ZNF592, ZFP69B, KLF4, NR2F2, ZNF544, ZNF791, NR2F1, TP53, PKNOX1, ZNF334, EGR2, ELF3, AR, ZBTB40, EGR1, ZBTB26, HSF1, RNF2, SCRT1, NOTCH3, NCOR1, CLOCK, BRD4, MAZ, ZNF24, AHR, RUNX1-3
  • Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000159212, ENSG00000159216,
  • Related loop: chr21:34700000-34725000~~chr21:35975000-36000000, chr21:34850000-34875000~~chr21:35975000-36000000, chr21:34875000-34900000~~chr21:35975000-36000000, chr21:34950000-34975000~~chr21:35975000-36000000, chr21:35507719-35509586~~chr21:35984012-35986224, chr21:35507734-35509545~~chr21:35984106-35986257, chr21:35850000-35875000~~chr21:35975000-36000000, chr21:35875000-35900000~~chr21:35975000-36000000,
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