- Basic information
- CohesinDB ID: CDBP00418274
- Locus: chr21-36004280-36006126
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Data sourse: GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE98367, GSE206145-NatGen2015, GSE120943, ENCSR153HNT
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Cell type: Fibroblast, HCT-116, Monocytes, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 38%,
"15_Quies": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: XBP1, KDM4B, FOXA1, RBFOX2, PBX2, ZNF90, ATF3, HNRNPUL1, ATF4, SMARCE1, ELF1, ZNF121, NFE2L2, ESR1, HNF1B, MED26, OCA2, HDAC8, CTCF, EP300, DPF2, E2F6, IRF4, E2F1, ZNF350, TEAD4, FOXA3, EHMT2, POU2F2, TOP2A, ID3, CTBP1, HOXC5, ERG, MYC, SMARCA4, ARID1B, GRHL3, GABPA, STAT3, NFE2, NFRKB, VDR, NR3C1, EZH2, GRHL2, PHF8, SPI1, IRF1, HDAC2, GATA2, FLI1, EP400, ZFX, RUNX2, PBX4, ARNT, ZNF48, SMAD4, SUPT5H, GMEB1, TEAD3, MYB, SCRT2, ZMYM3, VEZF1, L3MBTL2, REST, ZBTB7A, HNRNPLL, STAG1, PTTG1, NFATC3, CBX3, MTA3, CREM, FOXA2, WT1, ZBTB33, ZNF580, YY1, RELA, ZNF148, ZNF830, MGA, ZNF740, MAX, ZNF143, GATA1, NCOA3, NR2F2, BRD2, ZBTB40, EGR1, RNF2, BRD4, JUND, SCRT1, MAZ
- Target gene symbol (double-evidenced CRMs): SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops
- Related gene:
ENSG00000205670,
- Related loop:
chr21:34350000-34375000~~chr21:36000000-36025000,
chr21:34700000-34725000~~chr21:35975000-36000000,
chr21:34750000-34775000~~chr21:36000000-36025000,
chr21:34850000-34875000~~chr21:35975000-36000000,
chr21:34875000-34900000~~chr21:35975000-36000000,
chr21:34950000-34975000~~chr21:35975000-36000000,
chr21:35850000-35875000~~chr21:35975000-36000000,
chr21:35850000-35875000~~chr21:36000000-36025000,
chr21:35875000-35900000~~chr21:35975000-36000000,
chr21:36000000-36025000~~chr21:39125000-39150000,
chr21:7800000-7825000~~chr21:36000000-36025000,