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Basic information

CohesinDB ID: CDBP00418279

Locus: chr21-36020789-36021262

Data sourse: ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 62%, "14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GLIS1, NFATC3, POU2F2, CHD8, MEF2B, BCL6, CBX5, RBPJ, ZFX, GTF2B, WT1, ZBTB48, ZNF101, FOXA1, CBX8, MEF2C, CDK9, KDM1A, MEF2A, RELA, CREBBP, CHD4, JUNB, MYC, RUNX3, PRDM1, GRHL3, TCF4, ARNT, FOXK2, ATF2, BATF, APC, PAX5, SPIB, IKZF1, CDK8, MED1, TRIM28, KMT2A, MYB, BCLAF1, ZMYM3, KDM5B, EZH2, ZNF217, CTCF, TCF12, SPI1, EP300, TBX21, BHLHE40, BCL11A, NIPBL, TAF1, MNT, ZBTB40, GATA2, PAX8, IRF4, RBM25, ZNF146, ATF7, NOTCH3, IKZF2, BRD4, BCOR, TCF3, SMARCA5, RELB, ZNF528, SMC3, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216,

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Deatailed information for cohesin site CDBP00418279