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Basic information

CohesinDB ID: CDBP00418284

Locus: chr21-36037645-36037936

Data sourse: GSE206145-NatGen2015, GSE86191

Cell type: Fibroblast, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 60%, "5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CHD8, BCL6, FOXA2, ZNF263, BRD3, MYCN, PAF1, ZFX, KDM4C, XBP1, NKX2-2, ZBTB48, ZSCAN5A, WT1, TOP2A, ZNF16, TET2, ERG3, LEO1, CDK9, ERG2, KDM1A, YY1, MYC, CDK6, SP140, ZFP36, ARNT, PBX3, MAX, NKX3-1, SPIB, MED1, PDX1, NCOA3, EZH2, ZNF334, EGR2, CTCF, RBM22, SPI1, EP300, RBM25, IRF4, MXI1, BRD4, MAZ, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,RCAN1,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216,

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Deatailed information for cohesin site CDBP00418284