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Basic information

CohesinDB ID: CDBP00418289

Locus: chr21-36044664-36044983

Data sourse: ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 89%, "5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GLIS1, BCL6, BRD1, TBL1X, MYCN, FOXA2, ZFX, XBP1, ERF, DUX4, WT1, ZSCAN5A, FOXA1, ZBTB48, TET2, ERG3, STAT1, RBFOX2, ERG2, LEO1, HOXB13, ZFHX2, ZKSCAN1, HOXC5, ERG, RELA, HDGF, YY1, ZNF341, ATF3, RUNX2, CDK6, MYC, SP140, DAXX, HIF1A, ARNT, NKX2-1, ZNF48, PRDM9, GABPA, TAL1, TP63, NKX3-1, ZNF143, AGO2, FOS, DNMT3B, ZNF736, TLE3, NR3C1, CEBPB, CEBPG, TEAD1, ETV1, CREB1, PIAS1, TFAP2C, EZH2, ESR1, OCA2, KDM5B, ZNF334, EGR2, CTCF, RBM22, JUN, BAF155, SPI1, HNF4A, AR, GATA6, DPF2, GATA2, ASH2L, BRD4, SCRT1, FOXP1, AATF, SMC1, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RUNX1,CLIC6,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 35

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00418289