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Basic information

CohesinDB ID: CDBP00418295

Locus: chr21-36052795-36053372

Data sourse: GSE67783, GSE86191, GSE101921, GSE85526, ENCSR153HNT

Cell type: HCT-116, HEKn, HCAEC, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 59%, "5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRIM25, POU2F2, SMC1A, CHD8, TBL1X, MYCN, ZNF263, RUNX1T1, PAF1, ZFX, ZSCAN5D, XBP1, FOXA2, WT1, ZBTB48, MEF2C, DDX5, RBFOX2, LEO1, ERG, YY1, RELA, CREBBP, ZNF384, RUNX2, MYC, ZNF362, GRHL3, HIF1A, NKX2-1, STAT3, ETV6, TP63, MAX, ZNF143, CDK8, RCOR1, TAL1, PLAG1, TEAD3, OCA2, MRTFA, CTCF, TCF12, RBM22, SPI1, AR, ZBTB26, NOTCH3, BRD4, MAZ, SMC1, SMC3, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): SETD4,DOP1B,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000205670, ENSG00000185917, ENSG00000142197,

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Deatailed information for cohesin site CDBP00418295