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Basic information

CohesinDB ID: CDBP00418296

Locus: chr21-36053850-36054250

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 76%, "6_EnhG": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, GLIS1, CHD8, ZFX, WT1, ZSCAN5A, STAT1, RELA, MYC, STAT3, ZNF143, CDK8, DNMT3B, NR3C1, TEAD3, TP53, GRHL2, STAT5A, CTCF, RBM22, HNF4A, PAX3-FOXO1, AR, MXD3, E2F1, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,DOP1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000205670, ENSG00000185917, ENSG00000142197,

eachgene

Deatailed information for cohesin site CDBP00418296