- Basic information
- CohesinDB ID: CDBP00418298
- Locus: chr21-36056537-36057152
-
Data sourse: GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 75%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, CEBPA, MYCN, ZNF263, ZFX, XBP1, MEF2C, BCL3, LYL1, NEUROD1, RAD21, PBX4, OTX2, STAT3, GATA1, CDK8, FOS, DNMT3B, JMJD1C, CEBPB, NCOA3, EZH2, CTCF, SPI1, AR, FLI1, CLOCK, KMT2B, STAG1
- Target gene symbol (double-evidenced CRMs): DOP1B,SMIM11A,SETD4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 77
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000185917,
ENSG00000142197,
- Related loop:
chr21:34350000-34375000~~chr21:36050000-36075000,
chr21:36050000-36075000~~chr21:36200000-36225000,
chr21:36052399-36053789~~chr21:36111955-36113883,
chr21:36058447-36061428~~chr21:36111897-36113834,
chr21:36059236-36061877~~chr21:36111989-36114651,
chr21:36059285-36061312~~chr21:36104007-36105819,
chr21:36059285-36061312~~chr21:36112056-36113996,
chr21:36059311-36061185~~chr21:36103004-36105170,
chr21:36059311-36061185~~chr21:36112033-36114031,
chr21:36059312-36061200~~chr21:36104038-36105851,
chr21:36059347-36061711~~chr21:36102970-36104752,
chr21:36059348-36061289~~chr21:36103921-36105755,
chr21:36059348-36061289~~chr21:36112009-36113920,
chr21:36059365-36061258~~chr21:36112039-36113944,
chr21:36059394-36061226~~chr21:36112056-36114424,
chr21:36059613-36061297~~chr21:36103944-36105869,