Deatailed information for cohesin site CDBP00418299

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  • Basic information
  • CohesinDB ID: CDBP00418299
  • Locus: chr21-36058249-36058686
  • Data sourse: ENCSR153HNT
  • Cell type: K-562
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.989
  • Subunit: SA1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 36%, "4_Tx": 33%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, FOXA1, RXRB, MLL4, KDM3A, HDGF, MEN1, THAP1, MORC2, PAX5, ZNF320, SFPQ, TEAD1, ZNF121, SNAPC1, LMO2, OCA2, MED26, PITX3, ZNF561, ZNF577, E4F1, ARID5B, ZNF75A, SOX5, E2F4, DEK, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, ZNF263, POU5F1, BRD3, CTBP1, DUX4, STAT1, SAP130, ZNF485, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, TOP1, FOXK2, RCOR1, NR2F6, NFRKB, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ELF4, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, HCFC1, MXI1, DRAP1, NR2C2, RELB, EP400, RUNX1, HDAC1, NKX2-2, CEBPA, REPIN1, TET2, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, ELK1, ZBTB10, TFDP1, ATF2, FOXM1, SP2, SMARCB1, GMEB1, PML, PIAS1, SMAD1, ZNF331, NR1H2, C11orf30, EVI1, GSPT2, IKZF5, ARID2, AFF1, MBD2, ELL2, ETV4, NFATC3, CBFA2T2, MEF2B, ZNF207, CBX3, CREM, CHD2, PAF1, NFATC1, BRF2, ZSCAN16, WT1, MEF2C, CREB3L1, JUNB, NEUROD1, ZFP36, TCF4, PLAG1, ZFP69B, BCL11B, KLF4, ZBTB6, MED, EGR2, ZNF765, ELF3, ARID4B, RXR, EGLN2, HSF1, ZBTB26, NCOR1, ILF3, FOSL1, ZNF660, XBP1, KDM4B, ZNF101, PBX2, THRB, ATF3, ZFP64, RUNX3, WDHD1, CBFB, TP63, ZSCAN4, MITF, INTS11, MAF, JMJD1C, ELF1, RBM39, SNAI2, KLF10, SMAD5, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, DPF2, RYBP, SIX5, IRF4, DDX20, ZNF280A, PDX1, RBPJ, TFAP2C, MLX, ZNF239, ZSCAN21, ZBTB17, ZBTB48, ZNF317, MTA2, NONO, SRF, DDX5, NBN, KDM4A, ZNF2, HOMEZ, FOXP2, RXRA, NKX3-1, PRDM14, MIER3, TERF2, HNRNPH1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, TBL1XR1, KLF8, GRHL2, EBF3, KDM5A, ZBTB14, NFIL3, THAP11, SOX13, AFF4, POU4F2, ZNF770, ZMIZ1, ZNF18, CEBPZ, SP3, ARNT, BACH1, DAXX, ZNF48, ZEB2, NFYA, NCAPH2, ZNF10, HMGXB4, TEAD3, DIDO1, ZXDB, U2AF1, TAF7, KLF9, TBX5, USF1, BCL11A, SP1, ZNF479, ATF7, ASH2L, GLIS2, ZNF623, SMC3, MLLT1, STAG1, STAG2, ZNF394, AGO1, MTA3, EBF1, MAFF, ESR2, ZNF580, ZKSCAN1, BCL3, KDM1A, KLF7, KAT2B, BRG1, ZIC2, PCGF1, GATA3, KLF15, TAL1, NRIP1, ZNF143, AGO2, CBX2, TP53, ZSCAN22, NFKB1, PHOX2B, BRD2, PHF5A, KAT8, ARRB1, EGR1, RB1, TFIIIC, RNF2, BRD4, JUND, CUX1, ZSCAN23, IRF9, ZFP42, PGR, FANCL, SOX2, PATZ1, LEO1, UBTF, TFAP4, SIN3B, BMI1, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, SAP30, ESR1, ZNF217, ZNF524, KLF1, SOX4, E2F6, TRIM24, RFX5, U2AF2, GTF2F1, GLIS1, POU2F2, KDM4C, ASH1L, ZSCAN5A, ELK4, ERG2, SP4, TBP, HOXC5, OGG1, ETS1, MYC, ARID1B, KLF12, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, DNMT3B, EZH2, ZNF652, MRTFA, PHF8, SPI1, PCBP1, HDAC2, INTS13, GATAD2B, ZNF76, NFYB, ZNF554, NCOA2, ETV5, BCL6, SIN3A, ERG3, RARA, ZNF384, CREBBP, ZNF35, TAF15, NFYC, SMAD4, ZNF518A, CDK8, CSNK2A1, ZEB1, SPDEF, NCOA1, SREBF2, RBM22, HNF4A, NR4A1, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PTTG1, PPARG, TBL1X, ZNF692, GTF2B, ZNF30, JDP2, ZNF574, YY2, FOXO3, RELA, TARDBP, SKIL, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, AR, KMT2D, ZNF324, HEXIM1, AHR, DMAP1, FOSL2, ZNF391, HMG20A, E2F7, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, INSM2, CTCFL, PRDM1, KLF14, MECOM, CDX2, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, USF2, TCF12, BAF155, EP300, GATA6, GLI4, SOX6, CREB3, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, CDK7, ID3, RUNX1T1, HINFP, MLLT3, GATAD1, ARID3A, USP7, MIER1, ZNF341, RAD21, GRHL3, APC, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ZNF750, FEZF1, TFE3, EHF, HBP1, IRF1, SREBF1, ZGPAT, MRTFB, MYF5, ATF1, PTBP1, ZNF45A, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, IRF2, NOTCH1, RUNX2, CDK6, GATA4, OSR2, GR, ZNF184, NRF1, NR2C1, CHD1, FOS, SUPT5H, TGIF2, MED1, RFX2, KDM6B, MYB, CEBPD, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, PHF20, ZBTB7A, PHIP, TCF3, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, ZBTB33, CDK9, HOXB13, YY1, ZNF148, ASXL1, BRCA1, SP140, HIF1A, OTX2, ZNF449, GATA1, CEBPG, SP7, NCOA3, NR2F2, ZNF512, ZNF687, ZNF213, ZNF843, NFKBIZ, BHLHE40, PTRF, TAF1, ZNF579, ZBTB40, MYNN, CLOCK, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,DOP1B
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 21
  • Number of somatic mutations (non-coding): 3
  • Related genes and loops
  • Related gene: ENSG00000205670, ENSG00000185917, ENSG00000142197,
  • Related loop: chr21:34350000-34375000~~chr21:36050000-36075000, chr21:36050000-36075000~~chr21:36200000-36225000, chr21:36052399-36053789~~chr21:36111955-36113883, chr21:36058447-36061428~~chr21:36111897-36113834, chr21:36059236-36061877~~chr21:36111989-36114651, chr21:36059285-36061312~~chr21:36104007-36105819, chr21:36059285-36061312~~chr21:36112056-36113996, chr21:36059311-36061185~~chr21:36103004-36105170, chr21:36059311-36061185~~chr21:36112033-36114031, chr21:36059312-36061200~~chr21:36104038-36105851, chr21:36059347-36061711~~chr21:36102970-36104752, chr21:36059348-36061289~~chr21:36103921-36105755, chr21:36059348-36061289~~chr21:36112009-36113920, chr21:36059365-36061258~~chr21:36112039-36113944, chr21:36059394-36061226~~chr21:36112056-36114424, chr21:36059613-36061297~~chr21:36103944-36105869,
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