- Basic information
- CohesinDB ID: CDBP00418302
- Locus: chr21-36064608-36066514
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Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE67783, GSE72082, GSE138405, GSE86191, GSE98367, GSE206145, GSE101921, ENCSR054FKH, GSE120943, ENCSR153HNT, ENCSR917QNE
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Cell type: RPE, HMEC, Hela-Kyoto, HCT-116, Monocytes, Hep-G2, HCAEC, K-562, Liver, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, HMG20A, MEIS2, NME2, FOXA1, RBFOX2, PBX2, RXRB, KDM3A, TFAP4, HNRNPK, HDGF, ATF3, NFIC, RUNX3, PRDM1, ATF4, MXD4, BACH2, CDX2, MAF, TEAD1, ELF1, TRIM28, KLF6, NFE2L2, RCOR2, ZFP91, JUN, EP300, E4F1, SOX5, DPF2, DMAP1, TRIM24, IRF4, DDX20, E2F1, TEAD4, FOXA3, ZNF175, GATAD2A, EHMT2, PDX1, RBPJ, GTF2F1, ZBTB17, ZBTB48, DUX4, STAT1, NONO, GATAD1, SAP130, NBN, ARID3A, TBP, HNF4G, HOXC5, ERG, ETS1, ONECUT1, SMARCA4, ARID1B, RAD21, HOMEZ, RXRA, NKX2-1, GABPA, STAT3, ZNF614, IKZF1, RCOR1, LEF1, MIER3, NR2F6, NFE2, CEBPB, CREB1, ZNF652, GABPB1, ELF4, SPI1, MIXL1, EHF, HBP1, HDAC2, GATA2, ZNF644, FLI1, DRAP1, ZGPAT, SMARCA5, NFIL3, ETV5, CC2D1A, RUNX1, THAP11, BCL6, HDAC1, CEBPA, SOX13, ZFX, SMAD3, TBX3, SP5, TRIM22, SMARCC1, PRDM10, RARA, ZNF384, BRD9, PBX4, ARNT, ZNF48, SMAD4, CBFA2T3, FOXM1, PBX3, FOS, CDK8, ETV6, HMGXB4, TEAD3, MYB, ZMYM3, C11orf30, EVI1, MAFK, SP1, BCL11A, HNF4A, IKZF5, REST, ZBTB7A, RBM25, ASH2L, BCOR, TCF3, FOXP1, STAG1, STAG2, MLLT1, NFATC3, SKI, PPARG, CBX3, FOXA2, MEIS1, MIER2, MAFF, ZBTB33, MEF2C, ZNF580, KDM1A, YY1, RELA, JUNB, SP140, TCF4, BATF, TAL1, MAX, CEBPG, NR2F1, TP53, PKNOX1, ELF3, BRD2, KAT8, PHF5A, TBX21, NFKBIZ, ARID4B, TAF1, ZBTB40, EGR1, IKZF2, JUND, BRD4, ILF3, ZNF24, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): SETD4,DOP1B,SMIM11A,CBR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000185917,
ENSG00000159228,
ENSG00000142197,
- Related loop:
chr21:34350000-34375000~~chr21:36050000-36075000,
chr21:36050000-36075000~~chr21:36200000-36225000,
chr21:36058447-36061428~~chr21:36111897-36113834,
chr21:36059236-36061877~~chr21:36111989-36114651,
chr21:36059285-36061312~~chr21:36104007-36105819,
chr21:36059285-36061312~~chr21:36112056-36113996,
chr21:36059311-36061185~~chr21:36103004-36105170,
chr21:36059311-36061185~~chr21:36112033-36114031,
chr21:36059312-36061200~~chr21:36104038-36105851,
chr21:36059347-36061711~~chr21:36102970-36104752,
chr21:36059348-36061289~~chr21:36103921-36105755,
chr21:36059348-36061289~~chr21:36112009-36113920,
chr21:36059365-36061258~~chr21:36112039-36113944,
chr21:36059394-36061226~~chr21:36112056-36114424,
chr21:36059613-36061297~~chr21:36103944-36105869,
chr21:36069440-36070708~~chr21:36112102-36113990,