Deatailed information for cohesin site CDBP00418303

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  • Basic information
  • CohesinDB ID: CDBP00418303
  • Locus: chr21-36069428-36070759
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE165895, GSE67783, GSE86191, GSE138405, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE118494, ENCSR338DUC, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, ENCSR853VWZ, GSE131956, ENCSR676MJK, GSE111913, ENCSR054FKH, ENCSR537EFT, ENCSR153HNT, GSE68388, GSE126990, GSE50893, GSE126755, ENCSR000ECS, GSE38411
  • Cell type: MDM, RH4, OCI-AML-3, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, IMR-90, BCBL-1, K-562, HFFc6, H1-hESC, SNYDER, Monocytes, MB157, GM12878, GBM39, SK-N-SH, RT-112, HAP1, Macrophage, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HCAEC, Neutrophil, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 21% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.611
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "1_TssA": 28%, "2_TssAFlnk": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, FOXA1, RXRB, MLL4, KDM3A, IKZF3, MORC2, PAX5, TEAD1, LMO2, OCA2, MED26, PITX3, ZNF561, SOX5, PAX8, ZNF407, E2F4, ZNF674, ZNF528, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, BRD3, ZNF263, TOP2A, CTBP1, STAT1, SAP130, ERG, ZBTB8A, EZH1, SMARCA4, ZNF197, UBN1, RCOR1, NR2F6, CEBPB, CREB1, BMPR1A, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, HCFC1, ZNF785, RUNX1, CEBPA, NKX2-2, HDAC1, REPIN1, SP5, TRIM22, SMARCC1, PRDM10, ZXDC, CBX4, ELK1, ZBTB10, ATF2, SP2, SMARCB1, PML, ZNF331, PIAS1, C11orf30, GSPT2, IKZF5, ARID2, MBD2, ELL2, ETV4, NFATC3, CBFA2T2, CBX3, CHD2, NFATC1, WT1, MEF2C, CREB3L1, NEUROD1, PLAG1, KLF4, BCL11B, ZFP69B, ZNF281, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZBTB26, NCOR1, HSF1, ZNF316, FOSL1, SMARCA2, ZNF660, XBP1, ATF3, ZFP64, RUNX3, CBFB, DPF1, TP63, ZSCAN4, MITF, BACH2, ZNF467, MAF, INTS11, JMJD1C, ELF1, RBM39, SNAI2, KLF10, SMAD5, FUS, CTCF, JUN, MNT, ZBTB20, RYBP, IRF4, ZNF423, ZNF350, ZNF280A, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, ZNF317, NONO, SRF, DDX5, NBN, CHD4, KDM4A, HOMEZ, FOXP2, ZNF2, RXRA, NKX3-1, PRDM14, MIER3, VDR, NR3C1, ESRRA, KMT2A, ZBTB11, KLF8, GRHL2, EBF3, ZBTB14, NFIL3, THAP11, SOX13, AFF4, ZNF770, SP3, ARNT, BACH1, ZNF48, ZEB2, NFYA, PBX3, NCAPH2, MAFB, HMGXB4, TEAD3, ZXDB, KLF9, USF1, SP1, BCL11A, ASH2L, GLIS2, SMC3, STAG1, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MAFF, ZNF580, KLF7, KDM1A, BRG1, ZIC2, PCGF1, KLF15, TAL1, NRIP1, ZNF143, AGO2, TP53, ZSCAN22, BRD2, PHF5A, KAT8, ARRB1, TBX21, TFIIIC, RNF2, BRD4, JUND, ZSCAN23, CBX5, PGR, PATZ1, RING1B, TFAP4, MXD4, ZNF189, KLF6, NFE2L2, ESR1, KLF1, E2F6, TRIM24, GTF2F1, GLIS1, POU2F2, ZNF778, KDM4C, ZBTB1, ZSCAN5A, ELK4, ERG2, SP4, TBP, HNF4G, HOXC5, OGG1, ETS1, MYC, ARID1B, KLF12, NKX2-1, GABPA, STAT3, IKZF1, EZH2, ZNF652, MRTFA, PHF8, SPI1, PCBP1, HDAC2, INTS13, ZNF777, NFYB, ZNF554, ETV5, BCL6, SIN3A, ZBTB12, ERG3, RARA, ZNF384, NFYC, ZNF35, CREBBP, TAF15, SMAD4, ZNF518A, CBFA2T3, CDK8, ZEB1, ZMYM3, MAFK, HNF4A, REST, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, TBL1X, ZNF692, GTF2B, ZNF30, ZNF574, RELA, TARDBP, MGA, MAX, ZNF592, NR2F1, TCF7L2, KDM5B, NEUROG2, MYOD1, AR, ZNF324, HEXIM1, AHR, DMAP1, FOSL2, HMG20A, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, INSM2, NFIC, ZNF362, CTCFL, PRDM1, KLF14, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, USF2, TCF12, EP300, BAF155, GATA6, RAD51, E2F1, SMC1, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, GATAD1, GMEB2, ZNF341, RAD21, GRHL3, ZNF614, XRCC5, NFE2, ZNF639, ZNF750, ZNF93, FEZF1, TFE3, EHF, HBP1, IRF1, ZGPAT, MRTFB, SMC1A, MAFG, CBX1, SIRT6, ZNF335, ZFX, SMAD3, TWIST1, RUNX2, CDK6, OSR2, ZNF184, NRF1, FOS, SUPT5H, CHD1, MED1, CEBPD, KDM6B, ZNF3, L3MBTL2, SETDB1, KLF16, CCNT2, PHIP, TCF3, NELFA, FOXA2, RBBP5, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, ASXL1, ZNF610, SP140, HIF1A, OTX2, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF687, ZNF213, NFKBIZ, BHLHE40, PTRF, TAF1, ZNF579, CLOCK, MAZ, BRCA1
  • Target gene symbol (double-evidenced CRMs): CBR1,DOP1B,SMIM11A,SETD4
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 227
  • Number of somatic mutations (non-coding): 51
  • Related genes and loops
  • Related gene: ENSG00000205670, ENSG00000185917, ENSG00000159228, ENSG00000142197,
  • Related loop: chr21:34325000-34350000~~chr21:36075000-36100000, chr21:34350000-34375000~~chr21:36050000-36075000, chr21:34350000-34375000~~chr21:36075000-36100000, chr21:35950000-35975000~~chr21:36075000-36100000, chr21:36050000-36075000~~chr21:36200000-36225000, chr21:36069440-36070708~~chr21:36112102-36113990, chr21:36075000-36100000~~chr21:36175000-36200000, chr21:36075000-36100000~~chr21:38250000-38275000,
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