Deatailed information for cohesin site CDBP00418306

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  • Basic information
  • CohesinDB ID: CDBP00418306
  • Locus: chr21-36073158-36073998
  • Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE138405, ENCSR000BLS, ENCSR054FKH, ENCSR153HNT, ENCSR917QNE
  • Cell type: MCF-7, Hela-Kyoto, Hep-G2, K-562, Liver
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.944
  • Subunit: Mau2,SA1,Rad21,SA2
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 50%, "7_Enh": 13%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, PGR, HMG20A, ZSCAN5C, SOX2, HNF1A, FOXA1, HLF, RBFOX2, RXRB, PBX2, KDM3A, TFAP4, ATF3, PRDM1, MXD4, SMARCE1, TP63, MAF, ELF1, TEAD1, KLF6, KLF10, RCOR2, ESR1, TP73, CTCF, EP300, E4F1, MNT, SOX5, DPF2, DMAP1, ZNF528, RFX3, FOXA3, ZNF175, GATAD2A, RBPJ, EED, MLX, TFAP2C, ZSCAN5D, MYCN, POU5F1, TOP2A, MTA2, ZBTB48, ZSCAN5A, STAT1, GATAD1, SAP130, DDX5, NBN, HNF4G, ETS1, ONECUT1, MYC, EOMES, RFX1, HOMEZ, RAD21, SMARCA4, GRHL3, RXRA, GABPA, ZNF614, XRCC5, MIER3, DNMT3B, NR2F6, NR3C1, CREB1, EZH2, TBL1XR1, GRHL2, ZNF652, GABPB1, ZHX2, MIXL1, TFE3, HDAC2, ZNF644, DRAP1, ZGPAT, NFIL3, ETV5, THAP11, BCL6, MAFG, CEBPA, SOX13, ZFX, TET2, CBX8, SP5, SMARCC1, MYBL2, RARA, ZNF384, GATA4, GR, ARNT, BACH1, ZNF48, ATF2, SMAD4, MAFB, CHD1, HMGXB4, TEAD3, SCRT2, SMAD1, ZNF3, RBM22, USF1, SP1, HNF4A, IKZF5, REST, FOXP1, SMC3, STAG1, SKI, PPARG, FOXA2, CREM, MIER2, ZNF600, WT1, ZBTB33, TCF7, ZNF580, KDM1A, YY1, RELA, NEUROD1, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, CEBPG, NR2F2, TCF7L2, TP53, PHF5A, ELF3, KAT8, T, NFKBIZ, AR, ARID4B, BHLHE40, EGLN2, ZBTB26, RNF2, NOTCH3, BRD4, JUND, SCRT1, CUX1, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): CBR1,SETD4,DOP1B,SMIM11A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 8
  • Number of somatic mutations (non-coding): 8
  • Related genes and loops
  • Related gene: ENSG00000205670, ENSG00000185917, ENSG00000159228, ENSG00000142197,
  • Related loop: chr21:34325000-34350000~~chr21:36075000-36100000, chr21:34350000-34375000~~chr21:36050000-36075000, chr21:34350000-34375000~~chr21:36075000-36100000, chr21:35950000-35975000~~chr21:36075000-36100000, chr21:36050000-36075000~~chr21:36200000-36225000, chr21:36069440-36070708~~chr21:36112102-36113990, chr21:36075000-36100000~~chr21:36175000-36200000, chr21:36075000-36100000~~chr21:38250000-38275000,
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