Deatailed information for cohesin site CDBP00418311

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  • Basic information
  • CohesinDB ID: CDBP00418311
  • Locus: chr21-36079847-36080911
  • Data sourse: GSE85526, GSE206145-NatGen2015, ENCSR230ZWH, ENCSR917QNE
  • Cell type: Liver, Fibroblast, HEKn
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: Rad21,SA2,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 55%, "7_Enh": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, FOSL1, PGR, HMG20A, SOX2, MEIS2, XBP1, FOXA1, HLF, RBFOX2, PBX2, RXRB, UBTF, KDM3A, HDGF, ATF3, NFIC, ZFP64, MXD4, SMARCE1, PAX5, TP63, MITF, MAF, ELF1, TRIM28, TEAD1, RBM39, KLF6, NFE2L2, ESR1, MLL, OCA2, TP73, HDAC8, USF2, JUN, CTCF, TCF12, EP300, KLF1, E4F1, MNT, GATA6, SOX5, DPF2, PYGO2, E2F6, DMAP1, TRIM24, IRF4, CREB3, SOX6, DDX20, TEAD4, KMT2B, ZNF175, FOXA3, GATAD2A, PDX1, RBPJ, EED, MLX, EHMT2, POU2F2, CHD8, POU5F1, MYCN, TOP2A, ID3, CTBP1, MTA2, ZBTB17, ZBTB48, DUX4, STAT1, NONO, MLLT3, GATAD1, SAP130, NBN, ARID3A, SP4, DDX5, TBP, ERG, SMARCC2, ZNF341, MYC, ONECUT1, SMARCA4, ARID1B, HOMEZ, RAD21, RXRA, FOXK2, GABPA, STAT3, XRCC5, ZNF614, IKZF1, NFE2, RCOR1, ZNF639, NFRKB, LEF1, NR2F6, NR3C1, CEBPB, MIER3, ZNF750, STAT5B, KMT2A, CREB1, CCAR2, ZNF652, GABPB1, PHF8, SPI1, TFE3, MIXL1, ZSCAN2, IRF1, HDAC2, GATA2, ZNF644, MXD3, SIX2, FLI1, DRAP1, ZGPAT, NR2C2, NFIL3, EP400, ZNF554, ATF1, ETV5, CC2D1A, RUNX1, THAP11, GTF2A2, MAFG, SMC1A, CEBPA, HDAC1, LDB1, BCL6, SOX13, ZFX, ERG3, IRF2, CREBBP, ZBTB2, RARA, ZNF384, BRD9, ARNT, BACH1, ZNF48, ZEB2, SMAD4, CBFA2T3, PBX3, NR2C1, FOXM1, CDK8, HMGXB4, MAFB, FOS, MED1, ZNF584, GMEB1, TEAD3, DIDO1, MYB, SCRT2, TAF7, ZNF3, C11orf30, L3MBTL2, NCOA1, SETDB1, SREBF2, STAT5A, USF1, BCL11A, MAFK, SP1, HNF4A, NR4A1, IKZF5, REST, ZBTB7A, RBM25, ATF7, ASH2L, AFF1, BCOR, FOXP1, PHIP, SMC3, STAT2, STAG1, MLLT1, PTTG1, NFATC3, ZNF816, CBFA2T2, KLF13, ZNF316, FOXA2, MTA3, RBBP5, CBX3, CHD2, ZNF600, MIER2, GTF2B, MAFF, WT1, MEF2C, ZBTB33, CDK9, HOXB13, BCL3, ZKSCAN1, CREB3L1, YY1, ZNF580, RELA, KDM1A, ZNF589, TARDBP, JUNB, CHAMP1, TCF4, SKIL, OTX2, MGA, TAL1, MAX, GATA1, MTA1, PLAG1, KLF4, ZNF592, CEBPG, GFI1B, NR2F2, ZKSCAN8, ZNF512, NR2F1, TP53, PKNOX1, ELF3, BRD2, KAT8, PHF5A, ZFP28, TBX21, BHLHE40, AR, PAX3-FOXO1, ARID4B, TAF1, ZBTB40, NFKBIZ, PTRF, EGR1, MYNN, NCOR1, RNF2, BRD4, JUND, IKZF2, NOTCH3, ZBTB26, MAZ, ZNF440, IRF9, MEF2D, ZNF24, AHR
  • Target gene symbol (double-evidenced CRMs): DOP1B,SETD4,SMIM11A
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 3
  • Related genes and loops
  • Related gene: ENSG00000205670, ENSG00000185917, ENSG00000142197,
  • Related loop: chr21:34325000-34350000~~chr21:36075000-36100000, chr21:34350000-34375000~~chr21:36050000-36075000, chr21:34350000-34375000~~chr21:36075000-36100000, chr21:35950000-35975000~~chr21:36075000-36100000, chr21:36050000-36075000~~chr21:36200000-36225000, chr21:36075000-36100000~~chr21:36175000-36200000, chr21:36075000-36100000~~chr21:38250000-38275000,
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