- Basic information
- CohesinDB ID: CDBP00418314
- Locus: chr21-36087214-36088155
-
Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE25021, ENCSR917QNE, ENCSR000BKV, GSE116344, GSE106870, ENCSR000EEG, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR167MTG, GSE131956, GSE110061, GSE129526, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE83726, GSE50893
-
Cell type: H1-hESC, HCT-116, RH4, Hep-G2, CVB-hiPSC, GM12878, GM12891, HUES64, GBM39, SK-N-SH, K-562, Liver, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 56%,
"7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU2F2, SMC1A, CHD8, MAFG, ZNF316, ZBTB24, MYCN, SOX2, ZFX, ZNF317, XBP1, SMAD3, ZBTB48, WT1, HLF, SRF, ERG, YY1, RELA, NOTCH1, ATF3, RUNX2, EZH1, GATA4, SMARCA4, CTCFL, RAD21, AHR, GRHL3, ARNT, ATF2, XRCC5, MAX, ZNF143, CDK8, RCOR1, SNRNP70, MITF, MED1, NFE2, CEBPB, MYOG, TEAD3, NCOA3, SCRT2, TFAP2C, SMAD1, CCAR2, ESR1, TP53, KLF9, FEZF1, MYOD1, ELF3, CTCF, BRD2, BCL11A, SP1, JUN, HNF4A, AR, ATF7, RB1, ZBTB26, NOTCH3, JUND, BRD4, SCRT1, CLOCK, MAZ, NFIL3, SMC3, NCOR2, GATAD2A, STAG1, RBPJ, FOSL2
- Target gene symbol (double-evidenced CRMs): DOP1B,SMIM11A
- Function elements
- Human SNPs: Mitral_valve_prolapse
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops