- Basic information
- CohesinDB ID: CDBP00418321
- Locus: chr21-36117276-36118182
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Data sourse: ENCSR703TNG, GSE67783, ENCSR153HNT, GSE72082
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Cell type: K-562, MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, CBX1, ID3, ZFX, CTBP1, GTF2B, SMAD3, FOXA1, HLF, DDX5, CDK9, HOXB13, MPHOSPH8, ERG, KDM1A, YY1, NEUROD1, MYC, EZH1, SMARCA4, GR, RUNX3, ARNT, NFIB, HIF1A, PBX4, GRHL3, GATA3, GABPA, STAT3, SMARCE1, TP63, NKX3-1, MAX, IKZF1, RCOR1, MITF, ZNF143, MED1, PLAG1, ZNF750, ESRRA, CEBPB, KLF4, TEAD1, NR3C1, CREB1, PIAS1, KDM5B, ZNF217, ESR1, ZNF3, NCOA1, GRHL2, SETDB1, USF2, TRPS1, CTCF, USF1, EP300, BAF155, BCL11A, MNT, AR, SPI1, DPF2, YAP1, EGLN2, IRF4, ATF7, ASH2L, HSF1, RAD51, JUND, BRD4, CUX1, ZNF766, TEAD4, ZNF555, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:36100000-36125000,
chr21:34675000-34700000~~chr21:36100000-36125000,
chr21:34875000-34900000~~chr21:36100000-36125000,
chr21:35839536-35841080~~chr21:36112039-36113944,
chr21:35850000-35875000~~chr21:36100000-36125000,
chr21:35925000-35950000~~chr21:36100000-36125000,
chr21:35931786-35934458~~chr21:36111989-36114651,
chr21:35950000-35975000~~chr21:36100000-36125000,
chr21:36027315-36029474~~chr21:36112024-36114058,
chr21:36027381-36029536~~chr21:36112029-36113907,
chr21:36027554-36029658~~chr21:36112019-36114026,
chr21:36045268-36046896~~chr21:36112056-36113996,
chr21:36052399-36053789~~chr21:36111955-36113883,
chr21:36058447-36061428~~chr21:36111897-36113834,
chr21:36059236-36061877~~chr21:36111989-36114651,
chr21:36059285-36061312~~chr21:36112056-36113996,
chr21:36059311-36061185~~chr21:36112033-36114031,
chr21:36059348-36061289~~chr21:36112009-36113920,
chr21:36059365-36061258~~chr21:36112039-36113944,
chr21:36059394-36061226~~chr21:36112056-36114424,
chr21:36069440-36070708~~chr21:36112102-36113990,
chr21:36122381-36123542~~chr21:36140871-36142703,
chr21:36122898-36124126~~chr21:36134610-36136702,