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Basic information

CohesinDB ID: CDBP00418322

Locus: chr21-36120265-36121169

Data sourse: GSE111537, GSE67783, GSE86191, GSE165895

Cell type: OCI-AML-3, HCT-116, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, CHD8, PPARG, CEBPA, MTA3, RBBP5, POU5F1, ZFX, WT1, ZNF770, MEF2C, CDK9, PBX2, TBP, ERG, YY1, RELA, NOTCH1, LYL1, ETS1, AHR, THRB, SMARCA4, RUNX3, TCF4, RXRA, APC, ZNF143, CDK8, MITF, LEF1, MED1, PLAG1, CEBPG, JMJD1C, CEBPB, TEAD3, NR2F2, MYB, STAG1, EZH2, ESR1, OCA2, ZNF3, ZNF334, STAT5A, CTCF, TCF12, SPI1, BHLHE40, AR, TRIM24, CREB3, NOTCH3, BRD4, TCF3, MAZ, MLLT1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00418322