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Basic information

CohesinDB ID: CDBP00418323

Locus: chr21-36122832-36123472

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, ENCSR000ECS, GSE121355, GSE103477, GSE131606, GSE108869, GSE25021, ENCSR000BKV, GSE138405, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR703TNG, ENCSR199XBQ, GSE106870, GSE116344, ENCSR895JMI, GSE98367, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR853VWZ, GSE110061, GSE129526, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR748MVX

Cell type: MDM, RH4, GM2610, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, GM12890, HeLa-S3, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, Macrophage, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, A-549, HCAEC, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 17% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.611

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 92% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 66%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF426, ZNF697, ZNF101, ZNF221, ZNF529, ZFP64, ZNF362, CTCFL, ZNF444, PRDM12, ZNF189, MZF1, ZSCAN4, ZNF467, ZNF629, TEAD1, ZNF121, LMO2, ZNF23, CTCF, ZNF577, KLF1, E4F1, ZNF157, ZNF302, PRDM4, SMC1, TEAD4, ZNF555, GLIS1, ZNF778, ZBTB1, ZNF433, DUX4, ZNF138, SRF, SP4, AEBP2, ZBTB21, ERG, ZNF585B, ZNF341, ZBTB8A, SMARCA4, TSHZ1, RAD21, ZNF639, ZNF501, ESRRA, ZBTB11, ZNF560, ZNF514, FEZF1, ZNF292, ZNF664, ZNF202, GATA2, ZNF785, ZC3H11A, ZNF404, SMC1A, ZNF707, ZFP3, ZNF214, REPIN1, ZBTB12, ZFP37, ZNF770, ZNF16, ZNF654, ZNF18, PRDM10, OSR2, SP3, ARNT, ZNF781, HMGB2, ZNF518A, ZEB2, ZNF10, TEAD3, ZEB1, ZNF558, ZXDB, SCRT2, ZNF680, KLF9, USF1, BCL11A, REST, OVOL3, GLI2, ZNF548, SALL1, FOXP1, ZNF623, SMC3, ZNF704, ZNF34, STAG1, ZNF394, ZNF692, WT1, ZNF493, ZNF580, KLF7, HOXB13, ZNF19, ZNF266, ZNF510, ZNF610, GATA3, TAL1, GATA1, ZNF223, BCL11B, GFI1B, ZNF791, ZNF354C, ZNF530, TP53, ZNF213, ZNF547, ZNF140, ZNF843, AR, RBAK, ZNF324, ZNF366, ZBTB26, ZSCAN23, ZNF24

Target gene symbol (double-evidenced CRMs): SMIM11A,CBR3,CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216, ENSG00000159231,

eachgene

Deatailed information for cohesin site CDBP00418323