Deatailed information for cohesin site CDBP00418341

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  • Basic information
  • CohesinDB ID: CDBP00418341
  • Locus: chr21-36162643-36163290
  • Data sourse: GSE67783, ENCSR153HNT, GSE86191
  • Cell type: K-562, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 92% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 70%, "15_Quies": 17%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, XBP1, FOXA1, RXRB, PBX2, ZFHX2, KDM3A, TFAP4, ATF3, THRB, MXD4, MECOM, ZSCAN4, ZNF736, CDX2, JMJD1C, TEAD1, TRIM28, ELF1, KLF6, ETV1, RCOR2, ESR1, MLL, OCA2, USF2, CTCF, JUN, BAF155, EP300, L3MBTL4, MNT, GATA6, SOX5, SOX4, DMAP1, TRIM24, IRF4, E2F4, E2F1, ZNF528, TEAD4, KMT2B, FOXA3, ZNF175, GATAD2A, RBPJ, TFAP2C, MLX, GLIS1, POU2F2, CHD8, ZSCAN5D, ZNF263, POU5F1, TOP2A, CDK7, RUNX1T1, ID3, MYCN, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ZNF205, GATAD1, DDX5, SAP130, ERG2, ARID3A, TBP, HNF4G, ERG, ASCL1, ZNF341, MYC, HOMEZ, RAD21, RXRA, NKX2-1, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, IKZF1, NFE2, MIER3, NR2F6, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, CCAR2, EZH2, GRHL2, ZNF652, EBF3, TRPS1, GABPB1, ZHX2, SPI1, TFE3, MIXL1, HBP1, IRF1, HDAC2, INTS13, GATA2, ZNF644, MXD3, FLI1, DRAP1, ZGPAT, MXI1, NFIL3, ZIM3, NFYB, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, HDAC1, NKX2-2, CBX1, SIN3A, ZFX, SOX13, SMAD3, ZNF770, CBX8, ERG3, SP5, PRDM10, RARA, CREBBP, NOTCH1, ZNF133, NFYC, RUNX2, GATA4, OSR2, GR, ARNT, NRF1, ATF2, ZEB2, SMAD4, FOS, CDK8, HMGXB4, TGIF2, MED1, TEAD3, CEBPD, MYB, SCRT2, PIAS1, GTF3C2, L3MBTL2, EVI1, USF1, SP1, BCL11A, HNF4A, IKZF5, REST, ZNF479, ZBTB7A, ASH2L, PHIP, TCF3, FOXP1, MLLT1, STAG1, ETV4, ZNF394, SKI, PPARG, FOXA2, MTA3, CREM, ZNF600, MIER2, WT1, MEF2C, TCF7, ZBTB33, HOXB13, ZNF580, ZKSCAN1, KDM1A, YY1, RELA, SP140, TCF4, HIF1A, BHLHE22, GATA3, MAX, NRIP1, ZNF143, GATA1, TLE3, CEBPG, SP7, NCOA3, NR2F2, NEUROG2, NR2F1, TCF7L2, KDM5B, TP53, MYOD1, EGR2, ELF3, BRD2, KAT8, PHF5A, ARID4B, AR, BHLHE40, NFKBIZ, RXR, EGLN2, RB1, ZBTB26, NCOR1, BRD4, SCRT1, JUND, CLOCK, MAZ, SMAD4.1D12, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): CHAF1B,DOP1B,MORC3
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 1
  • Related genes and loops
  • Related gene: ENSG00000142197, ENSG00000159256, ENSG00000159259,
  • Related loop: chr21:36150000-36175000~~chr21:36300000-36325000, chr21:36150000-36175000~~chr21:36325000-36350000, chr21:36150000-36175000~~chr21:36375000-36400000, chr21:36150000-36175000~~chr21:39175000-39200000, chr21:36150000-36175000~~chr21:46175000-46200000, chr21:36155654-36157667~~chr21:36208890-36210845, chr21:36155654-36157667~~chr21:36259462-36261497,
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