- Basic information
- CohesinDB ID: CDBP00418344
- Locus: chr21-36166692-36167478
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, ENCSR879KXD, ENCSR153HNT, GSE108869
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Cell type: MCF-7, HCT-116, HeLa-S3, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 50%,
"4_Tx": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, MEIS2, FOXA1, PBX2, LYL1, ZFP64, PRDM1, SMARCE1, CDX2, ZNF467, JMJD1C, TEAD1, ZNF121, ETV1, ESR1, BAF155, EP300, GATA6, DPF2, TRIM24, SOX6, TEAD4, KMT2B, TFAP2C, ZSCAN5D, MYCN, ID3, CTBP1, ZBTB17, ZSCAN5A, STAT1, ERG, CHD4, ASCL1, MYC, SMARCA4, ARID1B, RXRA, NKX2-1, GABPA, NKX3-1, GFI1, RCOR1, IKZF1, CEBPB, CREB1, GRHL2, FEZF1, SPI1, HDAC2, GATA2, ZNF644, ZNF146, SIX2, RUNX1, HDAC1, CEBPA, AFF4, ZFX, TWIST1, SMARCC1, CREBBP, RUNX2, GATA4, ARNT, PBX4, ZEB2, CBFA2T3, CDK8, ZEB1, PML, MYB, PIAS1, ZNF3, L3MBTL2, SREBF2, KLF16, USF1, SP1, TFAP2A, HNF4A, REST, ZBTB7A, ASH2L, BCOR, FOXP1, PRDM6, SMC3, CBFA2T2, MTA3, CREM, HOXB13, RELA, NEUROD1, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, TLE3, NR2F2, NEUROG2, TCF7L2, KDM5B, PKNOX1, BHLHE40, AR, EGLN2, BRD4, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): DOP1B,CHAF1B,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 5
- Related genes and loops