- Basic information
- CohesinDB ID: CDBP00418350
- Locus: chr21-36175944-36176604
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Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 47%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, POU2F2, MAFG, FOXA2, NKX2-2, CREM, MYCN, TBL1X, RUNX1T1, ZFX, XBP1, ZBTB17, MAFF, ZBTB48, WT1, FOXA1, ERG3, DDX5, CDK9, ERG, YY1, RELA, ZBTB2, CREBBP, ASCL1, ATF3, MYC, EZH1, TCF4, BACH1, GRHL3, ZNF48, MAX, ZSCAN4, MAFB, NKX3-1, ZNF143, NFE2, NRIP1, MED1, BACH2, NCOA3, MYB, SNAI2, ZNF3, ESR1, OCA2, C11orf30, CTCF, MAFK, SPI1, HNF4A, AR, GATA2, BRD4, SCRT1, MAZ, SMC3, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): CBR1,SETD4,MORC3,DOP1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000185917,
ENSG00000159228,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:36075000-36100000~~chr21:36175000-36200000,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36325000-36350000,
chr21:36150000-36175000~~chr21:36375000-36400000,
chr21:36150000-36175000~~chr21:39175000-39200000,
chr21:36150000-36175000~~chr21:46175000-46200000,
chr21:36175000-36200000~~chr21:36350000-36375000,
chr21:36175000-36200000~~chr21:36575000-36600000,
chr21:36181050-36182274~~chr21:36329784-36332238,