- Basic information
- CohesinDB ID: CDBP00418354
- Locus: chr21-36185489-36190732
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE116868, ENCSR150EFU, ENCSR000ECS, GSE121355, GSE103477, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE67783, GSE86191, GSE138405, GSE76893, GSE51234, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR000BLS, GSE206145, ENCSR981FDC, ENCSR635OSG, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, GSE111913, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE126755, ENCSR748MVX
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Cell type: MDM, Liver, GP5d, HuCC-T1, RPE, Fibroblast, Ishikawa, HeLa-S3, K-562, H1-hESC, Monocytes, MB157, RT-112, Macrophage, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549, Neutrophil, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 21% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.767
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 46%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, ZBTB16, PGR, MAX, KMT2A, ZFX, GRHL3, ESR1, FOXP1, PBX3, CTCF, SPI1
- Target gene symbol (double-evidenced CRMs): DOP1B,SETD4,MORC3,CBR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 23
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185917,
ENSG00000159228,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:36075000-36100000~~chr21:36175000-36200000,
chr21:36152248-36154241~~chr21:36187568-36189319,
chr21:36175000-36200000~~chr21:36350000-36375000,
chr21:36175000-36200000~~chr21:36575000-36600000,
chr21:36181050-36182274~~chr21:36329784-36332238,
chr21:36187405-36189351~~chr21:36208897-36210863,
chr21:36187568-36189319~~chr21:36208696-36210781,