- Basic information
- CohesinDB ID: CDBP00418363
- Locus: chr21-36215461-36216010
-
Data sourse: GSE206145-NatGen2015, GSE67783
-
Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 53%,
"4_Tx": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF24, ZFP91
- Target gene symbol (double-evidenced CRMs): DOP1B,CHAF1B,MORC3,SETD4,CBR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000185917,
ENSG00000159228,
ENSG00000142197,
ENSG00000159256,
ENSG00000159259,
- Related loop:
chr21:36050000-36075000~~chr21:36200000-36225000,
chr21:36140628-36142797~~chr21:36208896-36211059,
chr21:36140770-36142598~~chr21:36208928-36210883,
chr21:36140789-36142775~~chr21:36208898-36210957,
chr21:36140792-36142611~~chr21:36208845-36210808,
chr21:36140799-36142837~~chr21:36208339-36210839,
chr21:36140808-36142792~~chr21:36208893-36211062,
chr21:36140818-36142825~~chr21:36208180-36210735,
chr21:36140822-36142823~~chr21:36208825-36210883,
chr21:36140824-36142795~~chr21:36208849-36210862,
chr21:36140828-36142593~~chr21:36208784-36210767,
chr21:36140836-36142645~~chr21:36208979-36210847,
chr21:36140837-36142525~~chr21:36208955-36210590,
chr21:36140838-36142714~~chr21:36208696-36210781,
chr21:36140838-36142786~~chr21:36208808-36211018,
chr21:36140843-36142531~~chr21:36208942-36210568,
chr21:36140848-36142815~~chr21:36208865-36210865,
chr21:36140849-36142584~~chr21:36208920-36210789,
chr21:36140850-36142837~~chr21:36208890-36210845,
chr21:36140852-36142557~~chr21:36208778-36210979,
chr21:36140862-36142780~~chr21:36208188-36210796,
chr21:36140863-36142602~~chr21:36208770-36210834,
chr21:36140866-36142633~~chr21:36208896-36210832,
chr21:36140870-36142745~~chr21:36209005-36210744,
chr21:36140871-36142703~~chr21:36208897-36210863,
chr21:36152011-36154258~~chr21:36208885-36210840,
chr21:36152043-36154290~~chr21:36208880-36210854,
chr21:36152093-36154114~~chr21:36208893-36211062,
chr21:36152185-36154228~~chr21:36208896-36210870,
chr21:36152191-36154260~~chr21:36208896-36210832,
chr21:36152213-36154154~~chr21:36208928-36210883,
chr21:36152221-36154080~~chr21:36208180-36210735,
chr21:36152227-36154127~~chr21:36208825-36210883,
chr21:36152242-36154206~~chr21:36208896-36211059,
chr21:36152248-36154241~~chr21:36208696-36210781,
chr21:36152259-36154196~~chr21:36208897-36210863,
chr21:36152272-36154246~~chr21:36208777-36210982,
chr21:36152322-36154109~~chr21:36208843-36210788,
chr21:36152382-36154180~~chr21:36208778-36210979,
chr21:36152395-36154141~~chr21:36208770-36210834,
chr21:36152396-36154049~~chr21:36208182-36211280,
chr21:36152486-36154104~~chr21:36208903-36211039,
chr21:36152494-36154153~~chr21:36208813-36210759,
chr21:36152513-36154017~~chr21:36208784-36210767,
chr21:36155171-36156841~~chr21:36208778-36210979,
chr21:36155462-36156722~~chr21:36208903-36211039,
chr21:36155654-36157667~~chr21:36208890-36210845,
chr21:36187405-36189351~~chr21:36208897-36210863,
chr21:36187568-36189319~~chr21:36208696-36210781,
chr21:36200000-36225000~~chr21:36325000-36350000,
chr21:36200000-36225000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36375000-36400000,
chr21:36208725-36210834~~chr21:36329820-36331841,
chr21:36208807-36210881~~chr21:36329776-36331875,
chr21:36208849-36210862~~chr21:36329821-36332549,
chr21:36208896-36211059~~chr21:36329784-36332238,
chr21:36208955-36210590~~chr21:36330185-36331807,
chr21:36209099-36210510~~chr21:36330219-36331784,
chr21:36209109-36210630~~chr21:36330220-36331778,