- Basic information
- CohesinDB ID: CDBP00418366
- Locus: chr21-36225295-36225749
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 50%,
"4_Tx": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, FOXA2, MYCN, ZFX, WT1, FOXA1, HOXB13, ERG, RELA, SP140, PRDM9, GABPA, NKX3-1, HDAC3, MED1, TLE3, TEAD1, CREB1, PIAS1, OCA2, TBX5, CTCF, BAF155, AR, NKX2-5, GATA2, ARID1A, ASH2L, BRD4, FOXP1, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): DOP1B,CBR3,SMIM11A,MORC3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:34350000-34375000~~chr21:36225000-36250000,
chr21:36050000-36075000~~chr21:36200000-36225000,
chr21:36125000-36150000~~chr21:36225000-36250000,
chr21:36200000-36225000~~chr21:36325000-36350000,
chr21:36200000-36225000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36375000-36400000,
chr21:36225000-36250000~~chr21:36325000-36350000,