- Basic information
- CohesinDB ID: CDBP00418370
- Locus: chr21-36230544-36231198
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
92% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 52%,
"5_TxWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, POU2F2, SMC1A, ZSCAN5D, MYCN, ZFX, XBP1, GTF2B, SMAD3, WT1, ZSCAN5A, ZBTB48, ZNF770, CBX8, SUZ12, ERG3, ERG2, TET2, ZNF19, RELA, YY1, BMI1, EZH1, SMARCA4, SP140, ZFP36, GRHL3, NKX2-1, PRDM9, STAT3, TP63, ZNF143, NCOA3, SCRT2, EZH2, KDM5B, TP53, OCA2, TP73, NCOA1, GRHL2, CTCF, IKZF5, FLI1, HSF1, RNF2, NCOR1, SCRT1, BRD4, CLOCK, SMC3, NCOR2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): MORC3,SMIM11A,DOP1B,CBR3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 105
- Number of somatic mutations (non-coding): 0
- Related genes and loops